1-Benzyl-4-phenylpiperidin-4-ol

1-Benzyl-4-phenylpiperidin-4-ol - Names and Identifiers

Name	1-Benzyl-4-phenylpiperidin-4-ol
Synonyms	BRN 0235839 Traxoprodil Impurity 2 Haloperidol impurities2 1-Benzyl-4-phenylpiperidin-4-ol 1-Benzyl-4-phenyl-4-piperidinol 4-Piperidinol, 1-benzyl-4-phenyl- 1-Benzyl-4-Hydroxy-4-phenylpiperidine 4-phenyl-1-(phenylmethyl)piperidin-4-ol 4-Piperidinol, 4-phenyl-1-(phenylMethyl)- 4-21-00-00653 (Beilstein Handbook Reference)
CAS	63843-83-4
EINECS	264-512-8
InChI	InChI=1/C18H21NO/c20-18(17-9-5-2-6-10-17)11-13-19(14-12-18)15-16-7-3-1-4-8-16/h1-10,20H,11-15H2

1-Benzyl-4-phenylpiperidin-4-ol - Physico-chemical Properties

Molecular Formula	C18H21NO
Molar Mass	267.37
Density	1.135
Melting Point	107-109℃
Boling Point	176 °C(Press: 0.1 Torr)
Flash Point	133.9°C
Vapor Presure	5.39E-08mmHg at 25°C
pKa	14.06±0.20(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.611

1-Benzyl-4-phenylpiperidin-4-ol - Introduction

It is an organic compound with the chemical formula C19H21NO. The following is a description of its nature, use, preparation and safety information:

Nature:
is a white to light yellow solid, it has a certain solubility, soluble in alcohol and ether. This compound has the structural characteristics of a piperidine ring and a benzyl group, as well as the presence of a hydroxyl group.

Use:
is an important organic intermediate, often used in the synthesis of drugs. It can be used in the preparation of various drugs, such as antidepressants, antipsychotics and sedative drugs.

Preparation Method:
The preparation method can be realized by the following steps:
1. N-benzyl -4-phenyl piperidine was synthesized by reaction of benzyl bromide with 4-phenyl piperidine;
2. Use sodium hydroxide or sodium methanol solution to reduce N-benzyl -4-phenyl piperidine to calcium.

Safety Information:
It is generally relatively safe under normal use conditions. However, as a chemical, it still requires proper handling and storage. During use, the laboratory's safe operation regulations should be observed. In addition, if there are any chemical hazards or side effects, wear appropriate personal protective equipment, such as gloves and goggles.

Last Update：2024-04-09 20:52:54