1-Benzyl-DL-Alpha-Proline

1-Benzyl-DL-Alpha-Proline - Names and Identifiers

Name	N-Benzyl-3-pyrrolidinecarboxylic acid
Synonyms	1-BENZYL-DL-SS-PROLINE 1-BENZYL-DL-BETA-PROLINE 1-Benzyl-DL-Alpha-Proline 1-BOC-3-PYRROLIDINE CARBOXYLIC ACID 1-Benzylpyrrolidine-3-carboxylic acid N-BENZYL-3-PYRROLIDINECARBOXYLIC ACID N-Benzyl-3-pyrrolidinecarboxylic acid 1-Benzyl-pyrrolidine-3-carboxylic acid 1-BENZYL-PYRROLIDINE-3-CARBOXYLIC ACID 3-Pyrrolidinecarboxylic acid, 1-(phenylMethyl)-
CAS	5731-18-0

1-Benzyl-DL-Alpha-Proline - Physico-chemical Properties

Molecular Formula	C12H15NO2
Molar Mass	205.25
Density	1.205±0.06 g/cm3(Predicted)
Melting Point	106-108 °C(Solv: methanol (67-56-1); acetone (67-64-1))
Boling Point	343.1±35.0 °C(Predicted)
pKa	3.83±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature

1-Benzyl-DL-Alpha-Proline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
Hazard Class	IRRITANT, HYGROSCOPI

1-Benzyl-DL-Alpha-Proline - Introduction

N-Benzyl-3-pyrrolidinecarboxylic acid(N-Benzyl-3-pyrrolidinecarboxylic acid) is an organic compound with the chemical formula C12H15NO2.

It is a white solid, soluble in some organic solvents such as ethanol and dimethyl ketone, insoluble in water. It has the structural characteristics of styrene and pyrrolidine, and is often alkaline in chemical reactions.

N-Benzyl-3-pyrrolidinecarboxylic acid is widely used in the field of drug synthesis as an intermediate in organic synthesis. It can be used to synthesize drugs such as antidepressants, anxiolytics, and analgesics. Its benzyl and pyrrolidine groups play an important role in the activity of the drug.

The compound can be produced by a benzylation reaction and a condensation reaction of pyrrolidine carboxylic acid. First, benzyl methanol is reacted with an alkali solution to obtain 1-benzylacetonitrile. Then, 1-benzylacetonitrile and pyrrolidine carboxylic acid were subjected to a condensation reaction to obtain N-Benzyl-3-pyrrolidinecarboxylic acid.

in the use of the process, should follow the routine laboratory safety procedures. Since there is less information on the disadvantages of this compound, more detailed safety information needs to be investigated before specific use and follow the chemical's use and storage recommendations.

Last Update：2024-04-09 21:01:54