1-Boc-3-((MethylaMino)Met...

1-Boc-3-((MethylaMino)Met... - Names and Identifiers

Name	1-Boc-3-((methylamino)methyl)azetidine
Synonyms	1-Boc-3-((MethylaMino)Met... 1-Boc-3-((methylamino)methyl)azetidine 3-[(Methylamino)methyl]-1-Boc-azetidine 3-[(Methylamino)methyl]azetidine, N1-BOC protected Tert-Butyl3-((methylamino)methyl)azetidine-1-carboxylate 3-(methylaminomethyl)-1-azetidinecarboxylic acid tert-butyl ester 3-[(Methylamino)methyl]azetidine-1-carboxylic acid tert-butyl ester 1-Azetidinecarboxylic acid, 3-[(methylamino)methyl]-, 1,1-dimethylethyl ester tert-Butyl 3-[(methylamino)methyl]azetidine-1-carboxylate, tert-Butyl 3-[(methylamino)methyl]azetane-1-carboxylate
CAS	1049730-81-5

1-Boc-3-((MethylaMino)Met... - Physico-chemical Properties

Molecular Formula	C10H20N2O2
Molar Mass	200.28
Density	1.023
Boling Point	262℃
Flash Point	112℃
Water Solubility	Slightly soluble in water.
pKa	10.23±0.10(Predicted)
Storage Condition	2-8°C
Sensitive	Irritant
MDL	MFCD08061965

1-Boc-3-((MethylaMino)Met... - Introduction

1-Boc-3-((methylamino)methyl)azetidine(1-Boc-3-((methylamino)methyl)azetidine), also known as BAM-Me (methyl-aminomethyl-maiodane-l-carboxylic acid tert-butyl ester), has the following properties, uses, methods of preparation and safety information:

1. nature:
-Chemical formula: C12H23NO3
-Molecular weight: 229.32g/mol
-Appearance: Colorless or light yellow liquid
-Melting point:-4°C
-Boiling Point: 151-153°C
-Solubility: Soluble in common organic solvents, such as ethanol, ether
-Stability: stable, but avoid contact with oxidants, strong acids and strong bases

2. use:
- BAM-Me can be used as an intermediate in organic synthesis, especially in amination and carboxylation reactions.
-can be used as a protecting group for protecting compounds containing amine groups, and protect the amine group to prevent interference from other functional groups when the synthesis reaction is selectively carried out.
-Due to its stability in solution and ease of operation, BAM-Me is also used in the field of synthesis of complex organic molecules and drug synthesis.

3. preparation method:
The synthesis of BAM-Me is usually carried out by the following steps:
-First, 3-amino -1-methyl-Majorane is reacted with tert-butanol to produce 3-((methylamino) methyl)-1-methyl-Majorane.
-Subsequently, the obtained product is reacted with tert-butyric anhydride (Boc2O) to produce 1-Boc-3-((methylamino)methyl)azetidine.

4. Safety Information:
- BAM-Me should follow safe operation and regulations whether it is used as a laboratory reagent or an industrial chemical.
-Wear appropriate protective equipment such as laboratory gloves, goggles and protective clothing when used.
-Avoid contact with skin and eyes, and pay attention to protective measures for ventilation.
-Store BAM-Me in a dry, cool place, away from fire and combustibles.

Last Update：2024-04-09 21:01:54