1-Boc-3-((MethylaMino)Met...
1-Boc-3-((methylamino)methyl)azetidine
CAS: 1049730-81-5
Molecular Formula: C10H20N2O2
1-Boc-3-((MethylaMino)Met... - Names and Identifiers
1-Boc-3-((MethylaMino)Met... - Physico-chemical Properties
| Molecular Formula | C10H20N2O2 |
| Molar Mass | 200.28 |
| Density | 1.023 |
| Boling Point | 262℃ |
| Flash Point | 112℃ |
| Water Solubility | Slightly soluble in water. |
| pKa | 10.23±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD08061965 |
1-Boc-3-((MethylaMino)Met... - Introduction
1-Boc-3-((methylamino)methyl)azetidine(1-Boc-3-((methylamino)methyl)azetidine), also known as BAM-Me (methyl-aminomethyl-maiodane-l-carboxylic acid tert-butyl ester), has the following properties, uses, methods of preparation and safety information:
1. nature:
-Chemical formula: C12H23NO3
-Molecular weight: 229.32g/mol
-Appearance: Colorless or light yellow liquid
-Melting point:-4°C
-Boiling Point: 151-153°C
-Solubility: Soluble in common organic solvents, such as ethanol, ether
-Stability: stable, but avoid contact with oxidants, strong acids and strong bases
2. use:
- BAM-Me can be used as an intermediate in organic synthesis, especially in amination and carboxylation reactions.
-can be used as a protecting group for protecting compounds containing amine groups, and protect the amine group to prevent interference from other functional groups when the synthesis reaction is selectively carried out.
-Due to its stability in solution and ease of operation, BAM-Me is also used in the field of synthesis of complex organic molecules and drug synthesis.
3. preparation method:
The synthesis of BAM-Me is usually carried out by the following steps:
-First, 3-amino -1-methyl-Majorane is reacted with tert-butanol to produce 3-((methylamino) methyl)-1-methyl-Majorane.
-Subsequently, the obtained product is reacted with tert-butyric anhydride (Boc2O) to produce 1-Boc-3-((methylamino)methyl)azetidine.
4. Safety Information:
- BAM-Me should follow safe operation and regulations whether it is used as a laboratory reagent or an industrial chemical.
-Wear appropriate protective equipment such as laboratory gloves, goggles and protective clothing when used.
-Avoid contact with skin and eyes, and pay attention to protective measures for ventilation.
-Store BAM-Me in a dry, cool place, away from fire and combustibles.
1. nature:
-Chemical formula: C12H23NO3
-Molecular weight: 229.32g/mol
-Appearance: Colorless or light yellow liquid
-Melting point:-4°C
-Boiling Point: 151-153°C
-Solubility: Soluble in common organic solvents, such as ethanol, ether
-Stability: stable, but avoid contact with oxidants, strong acids and strong bases
2. use:
- BAM-Me can be used as an intermediate in organic synthesis, especially in amination and carboxylation reactions.
-can be used as a protecting group for protecting compounds containing amine groups, and protect the amine group to prevent interference from other functional groups when the synthesis reaction is selectively carried out.
-Due to its stability in solution and ease of operation, BAM-Me is also used in the field of synthesis of complex organic molecules and drug synthesis.
3. preparation method:
The synthesis of BAM-Me is usually carried out by the following steps:
-First, 3-amino -1-methyl-Majorane is reacted with tert-butanol to produce 3-((methylamino) methyl)-1-methyl-Majorane.
-Subsequently, the obtained product is reacted with tert-butyric anhydride (Boc2O) to produce 1-Boc-3-((methylamino)methyl)azetidine.
4. Safety Information:
- BAM-Me should follow safe operation and regulations whether it is used as a laboratory reagent or an industrial chemical.
-Wear appropriate protective equipment such as laboratory gloves, goggles and protective clothing when used.
-Avoid contact with skin and eyes, and pay attention to protective measures for ventilation.
-Store BAM-Me in a dry, cool place, away from fire and combustibles.
Last Update：2024-04-09 21:01:54
