1-Boc-3-Methylene-pyrrolidine

1-Boc-3-Methylene-pyrrolidine - Names and Identifiers

Name	1-Pyrrolidinecarboxylic acid, 3-methylene-, 1,1-dimethylethyl ester
Synonyms	1-Boc-3-Methylenepyrrolid... 1-Boc-3-methylene-pyrrolidine 1-Boc-3-Methylene-pyrrolidine tert-butyl 3-Methylenepyrrolidine-1-carboxylate tert-butyl 3-methylidenepyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylic acid, 3-methylene-, 1,1-dimethylethy... 1-Pyrrolidinecarboxylic acid, 3-methylene-, 1,1-dimethylethyl ester 1-Pyrrolidinecarboxylic acid, 3-Methylene-, 1,1-diMethylethyl ester
CAS	114214-71-0

1-Boc-3-Methylene-pyrrolidine - Physico-chemical Properties

Molecular Formula	C10H17NO2
Molar Mass	183.25
Density	1.01±0.1 g/cm3(Predicted)
Boling Point	236.7±29.0 °C(Predicted)
pKa	-1.49±0.20(Predicted)
Storage Condition	2-8°C

1-Boc-3-Methylene-pyrrolidine - Introduction

1-Boc-3-Methylene-pyrrolidine is a compound whose chemical name is a-methyl. The following is a description of its nature, use, formulation and safety information:

Nature:
1-Boc-3-methylenepyrrolidine is a colorless to pale yellow liquid with a special odor. It is a relatively stable compound and can be dissolved in some organic solvents, such as alcohols and ethers.

Use:
1-Boc-3-methylenepyrrolidine is a widely used intermediate in organic synthesis. It can be added to the molecule as a protecting group (Boc protecting group) to prevent the reaction of specific functional groups. In organic synthesis, it is often used to synthesize amino acids, peptides, drugs and other organic molecules.

Method:
The synthesis of 1-Boc-3-methylenepyrrolidine is typically obtained by reacting 3-methylenepyrrolidine with a tert-butoxycarbonylating agent such as tert-butoxycarbonylammonium chloride. During the reaction, tert-butoxycarbonylammonium chloride introduces a Boc protecting group into the molecule.

Safety Information:
1-Boc-3-methylenepyrrolidine is a common compound in organic synthesis, but it still needs to be handled in a safe manner. The compound is potentially toxic and irritating to humans, so safe practices should be followed during use, including wearing appropriate protective equipment (such as gloves and glasses) and handling in a well-ventilated area.

In addition, pay attention to avoid skin and eye contact, and stay away from fire and flame. During handling and storage, it must be kept away from food, beverages and flammable materials.

Last Update：2024-04-09 20:52:54