1-Boc-4-(2-formylphenyl)piperazine - Names and Identifiers
1-Boc-4-(2-formylphenyl)piperazine - Physico-chemical Properties
Molecular Formula | C16H22N2O3
|
Molar Mass | 290.36 |
Density | 1.154±0.06 g/cm3(Predicted) |
Melting Point | 86-90°C(lit.) |
Boling Point | 425.3±40.0 °C(Predicted) |
Flash Point | 211°C |
Vapor Presure | 1.93E-07mmHg at 25°C |
Appearance | Solid |
pKa | 2.48±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.561 |
Physical and Chemical Properties | WGK Germany:3 |
1-Boc-4-(2-formylphenyl)piperazine - Risk and Safety
Risk Codes | R25 - Toxic if swallowed
R43 - May cause sensitization by skin contact
|
Safety Description | S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
Hazard Note | Irritant |
Hazard Class | 6.1 |
1-Boc-4-(2-formylphenyl)piperazine - Introduction
4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is an organic compound with the chemical formula C19H23N3O3.
Nature:
4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is a solid with a white to yellowish appearance. It is stable and not easily soluble in water, but soluble in some organic solvents such as ethanol, dimethylformamide and acetonitrile. Its melting point is about 75-80 degrees Celsius.
Use:
4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is an important organic synthesis intermediate. It can be used to synthesize drugs, pesticides and other organic compounds. For example, it can be used to synthesize some anti-tumor drugs and anti-platelet aggregation drugs.
Method:
The preparation of 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER can be carried out by the following steps: First, 4-hydroxybenzaldehyde and BOC-protected piperazine are reacted to generate 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER.
Safety Information:
When handling 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, you need to pay attention to the following safety precautions: Wear appropriate protective equipment, including chemical protective glasses, protective gloves and protective clothing. Avoid inhaling its dust or vapor, and maintain good ventilation. If contact with skin or eyes, rinse immediately and seek medical help. In addition, the compound should be kept away from fire and oxidizing agents, and remain sealed and moisture-proof during storage.
Last Update:2024-04-09 21:01:54