1-Boc-4-(3-aminopropyl)-piperazine

1-Boc-4-(3-aminopropyl)-piperazine - Names and Identifiers

Name	tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate
Synonyms	LogP 3-(4-Boc-piperazinyl)propanamine 1-BOC-4-(3-AMINOPROPYL)PIPERAZINE 1-Boc-4-(3-aminopropyl)-piperazine tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate 1-tert-Butyloxycarbonyl-4-(3-aminopropyl)-piperazine TERT-BUTYL 4-(3-AMINOPROPYL)PIPERAZINE-1-CARBOXYLATE 4-(3-AMINO-PROPYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Piperazinecarboxylicacid, 4-(3-aMinopropyl)-, 1,1-diMethylethyl ester
CAS	373608-48-1
InChI	InChI=1/C12H25N3O2/c1-12(2,3)17-11(16)15-9-7-14(8-10-15)6-4-5-13/h4-10,13H2,1-3H3

1-Boc-4-(3-aminopropyl)-piperazine - Physico-chemical Properties

Molecular Formula	C12H25N3O2
Molar Mass	243.35
Density	1.042±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	339.6±37.0 °C(Predicted)
Flash Point	159.2°C
Vapor Presure	9.1E-05mmHg at 25°C
pKa	10.39±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.493

1-Boc-4-(3-aminopropyl)-piperazine - Risk and Safety

Hazard Class

IRRITANT

1-Boc-4-(3-aminopropyl)-piperazine - Introduction

tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate is an organic compound. Its chemical formula is C14H28N2O2. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: White crystal or crystalline powder
-melting point: about 45-50 ℃
-Solubility: Soluble in some organic solvents, such as ethanol and chloroform

Use:
tert-butyl 4-(3-aminoppyl) piperazine-1-carboxylate is mainly used in the field of medicine, as a pharmaceutical intermediate. It can be used in the synthesis of bioactive compounds, such as anti-tumor drugs, antidepressants, etc., with a wide range of applications.

Preparation Method:
tert-butyl 4-(3-aminoppyl) piperazine-1-carboxylate can be prepared by the following steps:
1. tert-butyl alcohol is reacted with 4-piperazine methylamine to generate tert-butyl -4-piperazine methanol.
2. Preparation of 3-aminopropionaldehyde.
3. reacting 3-aminopropionaldehyde with tert-butyl-4-piperazine methanol to generate the tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate.

Safety Information:
-Harm to human body: Although there is no detailed toxicity study report for this compound, in general, safe operating procedures should be followed during use. Direct contact may cause irritation and allergic reactions.
-Environmental impact: The impact of this compound in the environment has not been studied in detail, but it should be handled and disposed of in accordance with the principles of environmental protection.

Please note that the use of this compound should follow appropriate operating procedures to ensure personal safety and safety of the experimental environment. This information is for reference only, please refer to the relevant chemical literature and laboratory practices for specific use.

Last Update：2024-04-09 15:17:57