1-Boc-4-(3-hydroxypropyl)piperazine

1-Boc-4-(3-hydroxypropyl)piperazine - Names and Identifiers

Name	4-(2-HYDROXY-PROPYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms	134665 1-Boc-4-(3-hydroxypropyl)piperazine tert-Butyl 4-(2-hydroxypropyl)piperazine-1-carboxylate 4-(2-HYDROXY-PROPYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(2-HYDROXYPROPYL)-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER 1-Piperazinecarboxylic acid, 4-(3-hydroxypropyl)-, 1,1-dimethylethyl ester
CAS	132710-90-8
InChI	InChI=1/C12H24N2O3/c1-12(2,3)17-11(16)14-8-6-13(7-9-14)5-4-10-15/h15H,4-10H2,1-3H3

1-Boc-4-(3-hydroxypropyl)piperazine - Physico-chemical Properties

Molecular Formula	C12H24N2O3
Molar Mass	244.33
Density	1.074±0.06 g/cm3(Predicted)
Melting Point	73-77 °C (lit.)
Boling Point	355.8±37.0 °C(Predicted)
Flash Point	168.998°C
Vapor Presure	0mmHg at 25°C
Appearance	Solid
pKa	15.10±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.491

1-Boc-4-(3-hydroxypropyl)piperazine - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
Hazard Class	6.1

1-Boc-4-(3-hydroxypropyl)piperazine - Introduction

1-tert-butoxycarbonyl-4-(3-hydroxypropane) piperazine is an organic compound with the chemical formula C13H22N2O3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-tert-Butoxycarbonyl-4-(3-hydroxypropane) piperazine is a white or off-white solid. It has a melting point and a boiling point at room temperature and is soluble in many organic solvents.

Use:
1-tert-butoxycarbonyl-4-(3-hydroxypropane) piperazine is an important organic synthesis intermediate. It can be used to synthesize drugs, pesticides, dyes and other organic compounds. For example, it can be used as an intermediate in the synthesis of antiviral drugs, and can also be used in the synthesis of fragrances and dyes.

Preparation Method:
The synthesis methods of 1-tert-butoxycarbonyl-4-(3-hydroxypropane) piperazine are various. One commonly used method is to obtain 1-tert-butoxycarbonyl-4-(3-hydroxypropane) piperazine by reacting piperazine with 1-chloroacetone. The specific reaction steps and conditions can be adjusted and optimized according to specific requirements.

Safety Information:
The safety of 1-tert-butoxycarbonyl-4-(3-hydroxypropane) piperazine needs to be evaluated on a case-by-case basis. In general, chemicals need to be used and handled in accordance with the appropriate safety procedures. Care should be taken to avoid inhalation, skin contact and ingestion of the compound. Appropriate protective measures should be used during operation, such as wearing chemical protective gloves and goggles. During storage and disposal, operations should be carried out in accordance with relevant laws and regulations. If an accident occurs, immediately take appropriate first aid measures and consult relevant professionals.

Last Update：2024-04-09 02:00:42