1-Boc-7-Amino-1H-indazole - Names and Identifiers
1-Boc-7-Amino-1H-indazole - Physico-chemical Properties
Molecular Formula | C12H15N3O2
|
Molar Mass | 233.27 |
Storage Condition | 2-8℃ |
1-Boc-7-Amino-1H-indazole - Introduction
acid, 7-aMino-, 1,1-dimethylethyl ester is an organic compound with the chemical formula C15H19N3O2. It is a white solid, soluble in organic solvents such as ethanol and dimethylformamide, and has high thermal and chemical stability.
acid, 7-aMino-, 1,1-dimethylethyl ester are often used as important intermediates in organic synthesis. It can be used to synthesize various indole compounds, such as drugs, natural products and functional materials. Its introduction can change the electronic properties and spatial configuration of the molecule, thereby affecting its chemical and biological activity.
The preparation methods of acid, 7-aMino-, 1,1-dimethylethyl ester are various, and common methods include:
1. Reaction of indole with N-Boc p-toluenesulfonate under alkaline conditions;
2. The reaction of indole with N-Boc-aminoalkane catalyzed by carbodiimide;
3. Indole reacts with N,N-dimethyl-N'-Boc-nitrosamine in the presence of diethyl dicarbonyl acetate and isopropylamine.
When using acid, 7-aMino, 1,1-dimethylethyl ester, you need to pay attention to its safety information. It may cause irritation to the eyes, skin, and respiratory tract, so personal protective measures, such as wearing goggles, protective gloves, and protective masks, are required. In addition, it should be stored in a cool and ventilated place to avoid contact with oxidants and heat sources. Correct understanding and correct operation is very important to ensure the safety of the experiment.
Last Update:2024-04-09 20:49:11