1-Boc-N-甲基-N-甲氧基-2-吡咯烷甲酰胺

1-Boc-N-甲基-N-甲氧基-2-吡咯烷甲酰胺 - Names and Identifiers

Name	1-Pyrrolidinecarboxylic acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester
Synonyms	1-Boc-2-[Methoxy(Methyl)carbaMoyl]pyrrolidine 2-(Methoxy-Methyl-Carbamoyl)-Pyrrolidine-1-Carboxylic Acid Tert-Butyl Ester 1-Pyrrolidinecarboxylic acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester
CAS	334872-14-9

1-Boc-N-甲基-N-甲氧基-2-吡咯烷甲酰胺 - Physico-chemical Properties

Molecular Formula	C12H22N2O4
Molar Mass	258.31
Storage Condition	Room Temprature

1-Boc-N-甲基-N-甲氧基-2-吡咯烷甲酰胺 - Introduction

acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester is an organic compound with the chemical formula C12H22NO2O4.

Nature:
-Appearance: Colorless to light yellow solid
-Solubility: Soluble in some organic solvents, such as dichloromethane, ethanol, etc.
-Melting point: About 80-85 ° C
-Storage conditions: should be stored in a dry, cool place

Use:
acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester is commonly used as a protecting group or an activating reagent in organic synthesis. It can be used to synthesize a variety of organic compounds, such as drugs, heterocyclic compounds, etc.

Method:
The synthesis method of acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester includes the following steps:
-reacting 1-pyrrole carboxylic acid with 2-amino methanol to generate 1-methoxy methyl 2-pyrrole carboxylic acid;
-The product is reacted with tert-butyl carbonate to generate 1-boc-n-methyl-n-methoxy-2-pyrrolecarboxamide.

Safety Information:
acid, 2-[(methoxymethylamino)carbonyl]-, 1,1-dimethylethyl ester is generally a low-toxic compound, but it is still necessary to comply with reasonable laboratory safety procedures, and properly preserved and disposed. During use, care should be taken to avoid inhalation, skin contact and ingestion. In case of contact, flush with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:56