1-BroMoheptadecafluorooctane
Perflubron
CAS: 423-55-2
Molecular Formula: C8BrF17
1-BroMoheptadecafluorooctane - Names and Identifiers
| Name | Perflubron |
| Synonyms | Perflubron Oxygent CA Oxygent HT Foralkyl Br 8 n-Perfluorooctyl Bromide 1-BroMoheptadecafluorooctane 1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane Octane, 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro- |
| CAS | 423-55-2 |
| EINECS | 207-028-4 |
| InChI | InChI=1/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 |
| InChIKey | WTWWXOGTJWMJHI-UHFFFAOYSA-N |
1-BroMoheptadecafluorooctane - Physico-chemical Properties
| Molecular Formula | C8BrF17 |
| Molar Mass | 498.962 |
| Density | 1.87g/cm3 |
| Melting Point | 6 °C |
| Boling Point | 144°C at 760 mmHg |
| Flash Point | 40.9°C |
| Water Solubility | Not miscible or difficult to mix in water. |
| Vapor Presure | 6.54mmHg at 25°C |
| Appearance | Form Viscous Solution, color Colorless to tan |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.296 |
| Physical and Chemical Properties | Bioactive Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) have anti-inflammatory activity and therefore reduce cytokine cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage to biological and abiotic systems and does not rely on their anti-inflammatory properties. |
| Use | The oxygen carrier in the emulsion can be used as a blood substitute. |
1-BroMoheptadecafluorooctane - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 2810 |
| WGK Germany | 3 |
| RTECS | RG8700000 |
| HS Code | 29037800 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 i.v. in female rats: 41 g/kg (Burgan) |
1-BroMoheptadecafluorooctane - Upstream Downstream Industry
1-BroMoheptadecafluorooctane - Nature
| Specific gravity | 1.930 |
| Merck | 14,7156 |
| BRN | 2016022 |
| EPA chemical information | 1-Bromoheptadecafluorooctane (423-55-2) |
Last Update：2024-04-10 22:29:15
1-BroMoheptadecafluorooctane - Security information
| Hazard Note | Irritant |
Last Update：2024-04-10 22:29:15
1-BroMoheptadecafluorooctane - Introduction
Perfluorooctyl bromide, also known as perflubron, is a perfluorinated compound with the chemical formula C8BrF17. It is a colorless, odorless liquid with high chemical inertness and thermal stability. Perflubron is commonly used as a solvent or carrier for fluorinated compounds and is used in the medical field as a component of artificial blood or respiratory gases. Due to its high solubility and oxygen-carrying capacity, perflubron has a wide range of applications in medical imaging, surgeries, and treatments. However, its toxicity and stability need to be carefully considered when using it.
Properties:
Perfluorooctyl bromide, also known as perflubron, is a colorless and transparent liquid with high chemical stability and inertness. It has a density of around 2.0 g/mL and a boiling point of approximately 142 degrees Celsius. Perflubron exhibits high solubility, particularly in oxygen and carbon dioxide, making it significant as a gas carrier in the medical field.
Uses:
1. Medical applications: Perflubron can be used as a component of artificial blood for transfusions, effectively carrying oxygen and helping maintain the body's oxygen supply.
2. Medical imaging: Perflubron can serve as a contrast agent in ultrasound imaging, enhancing contrast during medical imaging procedures.
3. Other applications: Perflubron can also be utilized as a drug carrier or solvent for drugs, as well as in specific chemical reactions in laboratory settings.
Synthesis:
Perflubron is generally synthesized through fluorination reactions, typically involving the reaction of octane or other hydrocarbons with fluorine gas and bromine gas. This process requires precise control of reaction temperature and pressure to ensure product quality and purity.
Safety:
Although perflubron plays a vital role in medical applications, its toxicity and stability should be taken seriously. Prolonged exposure or high-dose contact with perfluorinated compounds may have adverse effects on health. When handling perflubron, strict safety procedures should be followed to ensure proper handling and storage, reducing potential risks. In medical applications, perflubron should be used correctly based on clinical needs and the advice of medical professionals.
Last Update：2024-04-09 21:04:16
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View History
Raw Materials for 1-BroMoheptadecafluorooctane
Thiophene, 2-butyltetrahydro-, 1,1-dioxide
1-octanesulphonyl fluoride
DI-N-OCTYL SULFIDE
Perfluoro-1-octanesulfonyl fluoride
1-octanesulphonyl fluoride
DI-N-OCTYL SULFIDE
Perfluoro-1-octanesulfonyl fluoride
Downstream Products for 1-BroMoheptadecafluorooctane