1-Bromo-5-fluoro-2-methyl-3-nitrobenzene

1-Bromo-5-fluoro-2-methyl-3-nitrobenzene - Names and Identifiers

Name	1-Bromo-5-fluoro-2-methyl-3-nitrobenzene
Synonyms	2-Bromo-4-fluoro-6-n Bromo-4-fluoro-6-nit Bromo-4-fluoro-6-nitrotoluene 2-bromo-4-fluoro-6-nitrotoluene 2-BROMO-4-FLUORO-6-NITROTOLUENE 3-BroMo-5-fluoro-2-Methylnitrobenzene 1-Bromo-5-fluoro-2-methyl-3-nitrobenzene 1-bromo-5-fluoro-2-methyl-3-nitrobenzene benzene, 1-bromo-5-fluoro-2-methyl-3-nitro- Benzene, 1-broMo-5-fluoro-2-Methyl-3-nitro- 3-Bromo-5-fluoro-2-methylnitrobenzene, 1-Bromo-5-fluoro-2-methyl-3-nitrobenzene
CAS	502496-33-5
InChI	InChI=1/C7H5BrFNO2/c1-4-6(8)2-5(9)3-7(4)10(11)12/h2-3H,1H3

1-Bromo-5-fluoro-2-methyl-3-nitrobenzene - Physico-chemical Properties

Molecular Formula	C7H5BrFNO2
Molar Mass	234.02
Density	1.696±0.06 g/cm3(Predicted)
Boling Point	259.4±35.0 °C(Predicted)
Flash Point	110.7°C
Vapor Presure	0.021mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.57
MDL	MFCD03094189

1-Bromo-5-fluoro-2-methyl-3-nitrobenzene - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

1-Bromo-5-fluoro-2-methyl-3-nitrobenzene - Introduction

It is an organic compound whose chemical formula is C7H5BrFNO2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: It is a white crystalline solid.
-Melting point: about 54-56°C.
-Boiling point: about 232 ℃.
-Solubility: It is soluble in some organic solvents, such as ether and chloroform, but is almost insoluble in water.

Use:
As an organic synthesis intermediate, it is widely used in the manufacture of drugs and pesticides. It can be used in the synthesis of biologically active compounds and as a precursor for dyes and pigments.

Preparation Method:
It can be prepared by the following steps:
1. First, nitric acid is added to a solution of chlorobenzene to obtain nitrochlorobenzene.
2. Then, the nitrochlorobenzene and methyl lithium are reacted to obtain 2-methyl -4-nitrobenzene.
3. Next, 2-methyl-4-nitrobenzene was reacted with fluorine gas to obtain 2-methyl-4-fluoronitrobenzene.
4. Finally, 2-methyl -4-fluoronitrobenzene is reacted with bromine to obtain the final product.

Safety Information:
is an organic compound that should follow general laboratory safety practices. It may cause irritation and damage to the human body, so avoid skin contact, inhalation or ingestion. Appropriate personal protective equipment such as laboratory gloves, glasses and laboratory coats should be worn during operation. In case of accidental exposure or ingestion, seek medical help immediately.

Last Update：2024-04-09 21:01:54