Name | 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone |
Synonyms | 1-Chlorofrmyl-3-mesyl-2-imidaz 1-Chloroformyl-3-mesyl-2-imidazolidone 1-Chlorocarbonyl-3-Methylsulfonyl-2-Imidazolidone 3-chlorocarbonyl-1-methylsulfonyl-2-imidazolidone 1-CHLOROCARBONYL-3-METHYLSULFONYL-IMIDAZOLIDONE(2) 1-Chlorocarbonyl-3-methylsulfonyl-2-imidazoldinone 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone 3-Methanesulfonyl-2-Oxo-Imidazolidine-1-Carbonyl Chloride 3-(methylsulfonyl)-2-oxoimidazolidine-1-carbonyl chloride 1-Imidazolidinecarbonylchloride, 3-(methylsulfonyl)-2-oxo- |
CAS | 41762-76-9 |
EINECS | 255-540-1 |
InChI | InChI=1/C5H7ClN2O4S/c1-13(11,12)8-3-2-7(4(6)9)5(8)10/h2-3H2,1H3 |
InChIKey | ZWTPALHHEULAPI-UHFFFAOYSA-N |
Molecular Formula | C5H7ClN2O4S |
Molar Mass | 226.64 |
Density | 1.71±0.1 g/cm3(Predicted) |
Melting Point | 168-173 °C (lit.) |
Boling Point | 347.9±25.0 °C(Predicted) |
Flash Point | 164.2°C |
Vapor Presure | 5.21E-05mmHg at 25°C |
pKa | -2.60±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.594 |
Use | Is an important pharmaceutical intermediates, mainly used in the synthesis of Mezlocillin |
Hazard Symbols | C - Corrosive |
Risk Codes | 34 - Causes burns |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 3 |
HS Code | 29332900 |
Hazard Class | 8 |
Packing Group | II |
introduction | 1-chloroformyl-3-methylsulfonyl-2-imidazolidinone is a pharmaceutical intermediate that can be used to prepare mezlocillin sodium. Mezlocillin sodium is one of the national essential drugs. It is a downstream product of penicillin industrial salt and belongs to the third generation of semi-synthetic broad-spectrum antibiotics. Mezlocillin sodium has good acid, alkali and enzyme resistance, strong antibacterial effect on gram-positive cocci and bacilli, and has definite curative effect on bacterial infection such as Pseudomonas aeruginosa, Lebsiella pneumoniae, streptococcus. |
application | 1-chloroformyl -3-methanesulfonyl -2-imidazolidinone is an important pharmaceutical intermediate, mainly used in the synthesis of mezlocillin, etc. It is mainly used in the laboratory research and development process and the chemical and pharmaceutical production process. |
use | is an important pharmaceutical intermediate, mainly used in the synthesis of mezlocillin and other |