1-Ethynyl-3-phenylbenzene
1-Ethynyl-3-phenylbenzene
CAS: 58650-11-6
Molecular Formula: C14H10
1-Ethynyl-3-phenylbenzene - Names and Identifiers
| Name | 1-Ethynyl-3-phenylbenzene |
| Synonyms | 1,1'-Biphenyl, 3-ethynyl- 1-Ethynyl-3-phenylbenzene |
| CAS | 58650-11-6 |
1-Ethynyl-3-phenylbenzene - Physico-chemical Properties
| Molecular Formula | C14H10 |
| Molar Mass | 178.23 |
| Density | 1.06±0.1 g/cm3(Predicted) |
| Boling Point | 311.0±21.0 °C(Predicted) |
1-Ethynyl-3-phenylbenzene - Introduction
1-Ethynyl-3-phenylbenzene is an organic compound with the chemical formula C16H12. It is a colorless to pale yellow solid, poorly soluble in water, but soluble in organic solvents such as ether and chloroform.
1-Ethynyl-3-phenylbenzene has potential biological activity in the pharmaceutical field, so it is widely used in drug development and synthesis. It can also be used as a precursor for organic materials, such as the synthesis of liquid crystal materials and organic electronic materials. In addition, it can also be used in the synthesis of polymers and the preparation of dyes.
The preparation method of 1-Ethynyl-3-phenylbenzene can be obtained by reacting phenylacetylene and bromoacetylene. First, phenylacetylene and bromoacetylene react under the catalysis of copper oxychloride to form 3-bromo-1, 1 '-biphenyl. Then, 3-bromo-1, 1 '-biphenyl was subjected to elimination reaction with sodium hydroxide and aqueous ethanol to obtain 1-Ethynyl-3-phenylbenzene.
Regarding its safety information, 1-Ethynyl-3-phenylbenzene is generally safe under normal conditions of use. However, like most chemicals, it should be used correctly and in accordance with appropriate laboratory practices and safety measures. Contact with skin, eyes, and mucous membranes should be avoided, and caution should be exercised to prevent inhalation or ingestion. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
1-Ethynyl-3-phenylbenzene has potential biological activity in the pharmaceutical field, so it is widely used in drug development and synthesis. It can also be used as a precursor for organic materials, such as the synthesis of liquid crystal materials and organic electronic materials. In addition, it can also be used in the synthesis of polymers and the preparation of dyes.
The preparation method of 1-Ethynyl-3-phenylbenzene can be obtained by reacting phenylacetylene and bromoacetylene. First, phenylacetylene and bromoacetylene react under the catalysis of copper oxychloride to form 3-bromo-1, 1 '-biphenyl. Then, 3-bromo-1, 1 '-biphenyl was subjected to elimination reaction with sodium hydroxide and aqueous ethanol to obtain 1-Ethynyl-3-phenylbenzene.
Regarding its safety information, 1-Ethynyl-3-phenylbenzene is generally safe under normal conditions of use. However, like most chemicals, it should be used correctly and in accordance with appropriate laboratory practices and safety measures. Contact with skin, eyes, and mucous membranes should be avoided, and caution should be exercised to prevent inhalation or ingestion. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:54:55
