1-Fluoro-2-methyl-4-chlorobenzene
5-Chloro-2-fluorotoluene
CAS: 452-66-4
Molecular Formula: C7H6ClF
1-Fluoro-2-methyl-4-chlorobenzene - Names and Identifiers
| Name | 5-Chloro-2-fluorotoluene |
| Synonyms | AI3-52646 5-CHLORO-2-FLUOROTOLUENE 5-Chloro-2-fluorotoluene 2-FLUORO-5-CHLOROTOLUENE 1,4-difluoro-2-methylbenzene 1-Chloro-4-fluoro-3-methylbenzene 1-Fluoro-2-methyl-4-chlorobenzene Benzene, 4-chloro-1-fluoro-2-methyl- |
| CAS | 452-66-4 |
| EINECS | 207-204-0 |
| InChI | InChI=1/C7H6F2/c1-5-4-6(8)2-3-7(5)9/h2-4H,1H3 |
1-Fluoro-2-methyl-4-chlorobenzene - Physico-chemical Properties
| Molecular Formula | C7H6ClF |
| Molar Mass | 144.57 |
| Density | 1.188g/mLat 25°C(lit.) |
| Boling Point | 157-159°C752mm Hg(lit.) |
| Flash Point | 120°F |
| Vapor Presure | 21.8mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.188 |
| Color | Colorless to Almost colorless |
| BRN | 1931799 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.4995(lit.) |
1-Fluoro-2-methyl-4-chlorobenzene - Risk and Safety
| Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29036990 |
| Hazard Note | Irritant/Flammable |
| Hazard Class | 3 |
| Packing Group | III |
1-Fluoro-2-methyl-4-chlorobenzene - Introduction
5-Chloro-2-fluorotoluene, chemical formula C7H6ClF, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Boiling Point: 137-138°C
-Melting point:-20°C
-Density: 1.140g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether and benzene
Use:
- 5-Chloro-2-fluorotoluene is commonly used as a raw material and intermediate in organic synthesis.
-It can be used to synthesize compounds such as pesticides, medicines and dyes.
Preparation Method:
A common method of preparation is the synthesis of 5-Chloro-2-fluorotoluene by fluorination and chlorination.
1. First, 2-toluene is first reacted with chlorine and fluorine reactants to obtain 5-Chloro-2-fluorotoluene.
2. The reaction needs to be carried out at an appropriate temperature and conditions, and a suitable catalyst and solvent are used to promote the reaction.
Safety Information:
- 5-Chloro-2-fluorotoluene may be harmful to the human body, and contact with skin, eyes and mucous membranes should be avoided.
-Wear appropriate protective equipment, such as gloves, glasses and protective clothing.
-During operation, attention should be paid to prevent it from contacting open flames or high temperatures.
-Store it in a cool, dry and well-ventilated place, away from fire and oxidants.
-When using and handling this compound, please refer to the relevant safety data sheets and operating procedures, and follow laboratory and industrial safety procedures.
Nature:
-Appearance: colorless liquid
-Boiling Point: 137-138°C
-Melting point:-20°C
-Density: 1.140g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether and benzene
Use:
- 5-Chloro-2-fluorotoluene is commonly used as a raw material and intermediate in organic synthesis.
-It can be used to synthesize compounds such as pesticides, medicines and dyes.
Preparation Method:
A common method of preparation is the synthesis of 5-Chloro-2-fluorotoluene by fluorination and chlorination.
1. First, 2-toluene is first reacted with chlorine and fluorine reactants to obtain 5-Chloro-2-fluorotoluene.
2. The reaction needs to be carried out at an appropriate temperature and conditions, and a suitable catalyst and solvent are used to promote the reaction.
Safety Information:
- 5-Chloro-2-fluorotoluene may be harmful to the human body, and contact with skin, eyes and mucous membranes should be avoided.
-Wear appropriate protective equipment, such as gloves, glasses and protective clothing.
-During operation, attention should be paid to prevent it from contacting open flames or high temperatures.
-Store it in a cool, dry and well-ventilated place, away from fire and oxidants.
-When using and handling this compound, please refer to the relevant safety data sheets and operating procedures, and follow laboratory and industrial safety procedures.
Last Update：2024-04-09 21:01:54
