1-Fluoro-4-(isothiocyanatomethyl)benzene
m-Trifluoromethylbenzylamine
CAS: 2740-83-2
Molecular Formula: C8H8F3N
1-Fluoro-4-(isothiocyanatomethyl)benzene - Names and Identifiers
1-Fluoro-4-(isothiocyanatomethyl)benzene - Physico-chemical Properties
| Molecular Formula | C8H8F3N |
| Molar Mass | 175.15 |
| Density | 1.222g/mLat 25°C(lit.) |
| Melting Point | 176.5-178.5 °C |
| Boling Point | 93-97 °C (22 mmHg) |
| Flash Point | 160°F |
| Water Solubility | insoluble |
| Vapor Presure | 0.89mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.222 |
| Color | Clear colorless to yellow |
| BRN | 1102465 |
| pKa | 8.69±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.463(lit.) |
1-Fluoro-4-(isothiocyanatomethyl)benzene - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R22 - Harmful if swallowed R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 2 |
| HS Code | 29214980 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | III |
1-Fluoro-4-(isothiocyanatomethyl)benzene - Introduction
m-Trifluoromethylbenzylamine is an organic compound with the chemical formula C8H8F3N. It is a colorless to light yellow liquid or solid with a benzene ring and a trifluoromethyl group.
m-Trifluoromethylbenzylamine has a wide range of applications in medicinal chemistry and organic synthesis. It can be used as an intermediate in the synthesis of drugs, such as the synthesis of amino acids, peptide drugs, etc. It can also be used for synthetic pesticides and insecticides, with insecticidal and bactericidal effects.
The method for preparing m-Trifluoromethylbenzylamine can be obtained by reacting benzylamine with trifluoromethyl mercaptan. First, benzylamine is reacted with trifluoromethyl mercaptan under suitable reaction conditions to form m-Trifluoromethylbenzylamine.
Regarding the safety information of m-Trifluoromethylbenzylamine, it should be noted that it is irritating, and contact with skin and eyes can cause inflammation and irritation. When in use, need to wear protective gloves, goggles and other personal protective equipment, to ensure that the operation in a well-ventilated place. Avoid contact with oxidizing agents and strong acids during storage and handling, and follow relevant safe operating procedures.
m-Trifluoromethylbenzylamine has a wide range of applications in medicinal chemistry and organic synthesis. It can be used as an intermediate in the synthesis of drugs, such as the synthesis of amino acids, peptide drugs, etc. It can also be used for synthetic pesticides and insecticides, with insecticidal and bactericidal effects.
The method for preparing m-Trifluoromethylbenzylamine can be obtained by reacting benzylamine with trifluoromethyl mercaptan. First, benzylamine is reacted with trifluoromethyl mercaptan under suitable reaction conditions to form m-Trifluoromethylbenzylamine.
Regarding the safety information of m-Trifluoromethylbenzylamine, it should be noted that it is irritating, and contact with skin and eyes can cause inflammation and irritation. When in use, need to wear protective gloves, goggles and other personal protective equipment, to ensure that the operation in a well-ventilated place. Avoid contact with oxidizing agents and strong acids during storage and handling, and follow relevant safe operating procedures.
Last Update：2024-04-09 21:01:54
