Name | 2-Nitrobenzaldehyde |
Synonyms | 2-NBA 2-Nitrobenzaldehyd 2-Nitobenzaldehyde o-nitro-benzaldehyd o-Nitrobenzyldehyde 2-nitro-benzaldehyd o-nitrobenzaldehyde 2-Nitrobenzaldehyde o-nitro benzaldehyde Benzaldehyde,2-nitro- Benzaldehyde, o-nitro- 2-ForMyl-3-nitrobenzene ortho nitrobenzaldehyde 1-ForMyl-2-nitrobenzene ortho nitro benzaldehyde 2-Nitrobenzenecarboxaldehyde |
CAS | 552-89-6 |
EINECS | 209-025-3 |
InChI | InChI=1/C7H5NO3/c9-5-6-3-1-2-4-7(6)8(10)11/h1-5H |
Molecular Formula | C7H5NO3 |
Molar Mass | 151.12 |
Density | 1,284 g/cm3 |
Melting Point | 42-44°C(lit.) |
Boling Point | 153°C23mm Hg(lit.) |
Flash Point | >230°F |
Water Solubility | Insoluble in water. |
Solubility | Can volatilize with water vapor. Easily soluble in ethanol, benzene and ether, slightly soluble in water. |
Vapor Presure | 0.0078mmHg at 25°C |
Vapor Density | 5.2 (vs air) |
Appearance | Pale yellow crystalline powder |
Color | Yellow |
Merck | 14,6586 |
BRN | 742624 |
Storage Condition | Store below +30°C. |
Sensitive | Air Sensitive |
Refractive Index | 1.5800 (estimate) |
MDL | MFCD00007132 |
Physical and Chemical Properties | melting point 41-44°C boiling point 153°C (23 torr) |
Use | Used as a pharmaceutical intermediate for the production of |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R68 - Possible risk of irreversible effects |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. |
WGK Germany | 2 |
RTECS | CU7300000 |
FLUKA BRAND F CODES | 8 |
TSCA | Yes |
HS Code | 29130000 |
Hazard Note | Irritant |
Raw Materials | 2-Nitrotoluene Hydrogen peroxide Hydrogen peroxide Nitric acid Bromine |
Downstream Products | Nifedipine |
bright yellow needle-like crystals, with the flavor of benzaldehyde, can be volatilized with water vapor. Melting point of 43~44 ℃, boiling point of 153 ℃(3. lkPa). Soluble in ethanol, ether, benzene, water-soluble, flash point> 110 ℃, and the vigorous reaction of pyrrole.
O-nitrotoluene was used as a starting material and prepared by the following two methods.
This product can make anti-angina drug nitropyridine (Xin Tong Ding); Its nitro group is reduced to amino group to become O-aminobenzaldehyde, which can be used to synthesize quinoline ring drugs.
LogP | 1.74 at 25℃ |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Use | This product is an organic synthesis intermediate, used in the pharmaceutical industry to manufacture the anti-angina drug nitropyridine (Xintongding); the nitro group is reduced to amino After the group becomes o-aminobenzaldehyde, quinoline ring drugs can be synthesized from it. Organic synthetic intermediates, used in the pharmaceutical industry to manufacture the anti-angina drug nitropyridine (Xintongding). The nitro group is reduced to amino group and then becomes o-aminobenzaldehyde, which can be used to synthesize quinoline ring drugs. Determination of isopropanol, acetone and methyl ketone. Organic synthesis. Used as a pharmaceutical intermediate for the production of Xintongding |
production method | using o-nitrotoluene as raw material, it can be produced by the following two methods. 1. o-nitrotoluene reacts with acetic anhydride and is obtained by hydrolysis. 2. O-nitrotoluene is obtained by nitration and oxidation. |
spontaneous combustion temperature | 200°C (Lit.) |