1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline(IIDQ) - Names and Identifiers
Name | IIDQ
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Synonyms | IIDQ LABOTEST-BB LT00440912 iidq (2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydro N-ISOBUTOXYCARBONYL-2-ISOBUTOXY-1,2 DIHYDROQUINONE 1-ISOBUTOXYCARBONYL-2-ISOBUTOXY-1,2-DIHYDROQUINOLINE 2-ISOBUTOXY-1-ISOBUTOXYCARBONYL-1,2-DIHYDROQUINOLINE 2-Isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline 1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline Isobutyl 1,2-dihydro-2-isobutoxy-1-quinoline-carboxylate ISOBUTYL 1,2-DIHYDRO-2-ISOBUTOXY-1-QUINOLINE-CARBOXYLATE Iidq 1-Isobutoxycarbonyl-2-Isobutoxy-1,2-Dihydroquinoline 1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline(IIDQ) 2-methylpropyl 2-(2-methylpropoxy)quinoline-1(2H)-carboxylate 2-methylpropyl (2R)-2-(2-methylpropoxy)quinoline-1(2H)-carboxylate 2-methylpropyl (2S)-2-(2-methylpropoxy)quinoline-1(2H)-carboxylate (2R)-2-(2-methylpropoxy)-2H-quinoline-1-carboxylic acid 2-methylpropyl ester
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CAS | 38428-14-7
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EINECS | 253-925-9 |
InChI | InChI=1/C18H25NO3/c1-13(2)11-21-17-10-9-15-7-5-6-8-16(15)19(17)18(20)22-12-14(3)4/h5-10,13-14,17H,11-12H2,1-4H3/t17-/m1/s1 |
1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline(IIDQ) - Physico-chemical Properties
Molecular Formula | C18H25NO3
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Molar Mass | 303.4 |
Density | 1.022g/mLat 25°C(lit.) |
Melting Point | 140-142℃0.2 mmHg (lit.) |
Boling Point | 140-142°C0.2mm Hg(lit.) |
Flash Point | >230°F |
Vapor Presure | 6.53E-06mmHg at 25°C |
BRN | 1543065 |
pKa | -1.40±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.523(lit.) |
MDL | MFCD00006702 |
1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline(IIDQ) - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
R68 - Possible risk of irreversible effects
R45 - May cause cancer
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Safety Description | S23 - Do not breathe vapour.
S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37 - Wear suitable protective clothing and gloves.
S53 - Avoid exposure - obtain special instructions before use.
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WGK Germany | 3 |
HS Code | 29334900 |
1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline(IIDQ) - Introduction
IIDQ(IIDQ) is an organic synthesis reagent. The following is a description of the nature, use, method and safety information of IIDQ:
Nature:
IIDQ is a white to off-white crystalline powder, which can be dissolved in water and common organic solvents (such as dichloromethane, dimethylformamide, etc.). It is stable in the air, but may decompose when damp.
Use:
IIDQ is mainly used as an oxidant and carbonyl activating reagent in organic synthetic chemistry. It can oxidize numerous organic compounds, including alcohols, ketones, aldehydes, and carboxylic acids, without generating waste. IIDQ is widely used in the synthesis of active compounds, pharmaceutical intermediates and natural products.
Preparation Method:
The synthesis of IIDQ is mainly achieved through the following steps: First, 1,2-dihydro-2-isobutanol and quinoline -1-carboxylic acid isobutyl ester are reacted to generate an esterification product. The higher purity IIDQ can then be obtained by further reaction and crystallization purification.
Safety Information:
IIDQ has good safety under reasonable operation. However, as a chemical agent, it still has a certain degree of danger. When using IIDQ, wear appropriate protective equipment, avoid inhalation of its powder or solution and avoid contact with skin and eyes. During the operation, the safe operation procedures should be observed, and the operation should be carried out in a well-ventilated place. If inhaled or exposed by mistake, seek medical help immediately.
Last Update:2024-04-09 21:01:54