1-N-BOC-4-(3-CARBOXY-4-NITROPHENYL)PIPERAZINE

1-N-BOC-4-(3-CARBOXY-4-NITROPHENYL)PIPERAZINE - Names and Identifiers

Name	1-N-Boc-4-(3-Carboxy-4-Nitrophenyl)Piperazine
Synonyms	1-N-Boc-4-(3-Carboxy-4-Nitrophenyl)Piperazine 1-N-BOC-4-(3-CARBOXY-4-NITROPHENYL)PIPERAZINE 5-[4-(tert-butoxycarbonyl)piperazin-1-yl]-2-nitrobenzoic acid 1-Piperazinecarboxylic acid, 4-(3-carboxy-4-nitrophenyl)-, 1-(1,1-dimethylethyl) ester
CAS	183622-36-8
InChI	InChI=1/C16H21N3O6/c1-16(2,3)25-15(22)18-8-6-17(7-9-18)11-4-5-13(19(23)24)12(10-11)14(20)21/h4-5,10H,6-9H2,1-3H3,(H,20,21)

1-N-BOC-4-(3-CARBOXY-4-NITROPHENYL)PIPERAZINE - Physico-chemical Properties

Molecular Formula	C16H21N3O6
Molar Mass	351.35
Density	1.329g/cm³
Boling Point	555.622°C at 760 mmHg
Flash Point	289.83°C
Vapor Presure	0mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.583

1-N-BOC-4-(3-CARBOXY-4-NITROPHENYL)PIPERAZINE - Introduction

1-N-Boc-4-(3-carboxyy-4-nitrophenyl) Piperazine is an organic compound with the following properties:

1. Appearance: A white or off-white crystalline solid.
2. Molecular formula: C19H23N3O6.
3. Molecular weight: 397.41g/mol.
4. Melting point: About 149 ℃.
5. Solubility: Soluble in ethanol and dichloromethane, insoluble in water.

Use:
1-N-Boc-4-(3-carboxyy-4-nitrophenyl) Piperazine is an important organic synthesis intermediate and has a wide range of applications in pharmaceutical chemistry.
It is often used to prepare various drug compounds, such as anticancer drug molecules, antibiotics and other bioactive compounds.

Method:
The preparation method of 1-N-Boc-4-(3-carboxyy-4-nitrophenyl) Piperazine is more complicated, and it is generally synthesized by chemical reaction. A common preparation method is:
Firstly, 3-nitro-4-nitrobenzoic acid was obtained by nitration reaction with nitric acid as raw material. 3-Nitro-4-nitrobenzoic acid is then reacted with Piperazine to yield 1-N-Boc-4-(3-Carboxy-4-Nitrophenyl)Piperazine.

Safety Information:
1-N-Boc-4-(3-carboxyy-4-nitrophenyl) Piperazine is required to strictly comply with relevant laboratory safety practices during storage and use.
It may be irritating to the human body, and inhalation or contact with skin and eyes should be avoided. Wear appropriate protective equipment such as lab gloves, goggles and protective clothing.
At the same time, avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.
When disposing of waste, it needs to be sorted and disposed of in accordance with local regulations.

Last Update：2024-04-09 21:11:58