1-N-Boc-4-(Aminoethyl)-piperidine - Names and Identifiers
1-N-Boc-4-(Aminoethyl)-piperidine - Physico-chemical Properties
Molecular Formula | C12H24N2O2
|
Molar Mass | 228.33 |
Density | 1.010±0.06 g/cm3(Predicted) |
Boling Point | 316.0±15.0 °C(Predicted) |
Flash Point | 144.9°C |
Vapor Presure | 0.000422mmHg at 25°C |
pKa | 10.43±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.481 |
1-N-Boc-4-(Aminoethyl)-piperidine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
UN IDs | UN2811 |
Hazard Class | IRRITANT |
1-N-Boc-4-(Aminoethyl)-piperidine - Introduction
4-(2-Aminoethyl)-1-Boc-piperidine is an organic compound with the chemical formula C12H22N2O2. It has some of the following properties:
1. Appearance: 4-(2-Aminoethyl)-1-Boc-piperidine is a colorless to pale yellow solid.
2. Solubility: It is soluble in most organic solvents, such as ethanol, chloroform and dichloromethane. It has poor solubility in water.
3. Thermal stability: Under normal conditions, it is relatively stable, but it will decompose at high temperatures.
4. Storage conditions: 4-(2-Aminoethyl)-1-Boc-piperidine should be stored in a dry, cool place, avoid direct sunlight.
4-(2-Aminoethyl)-1-Boc-piperidine is mainly used as an intermediate in organic synthesis. It can be used in the preparation of anticancer drugs, hormone drugs and other biologically active compounds. It has a wide range of applications in the field of drug development and organic synthesis.
The method for preparing 4-(2-Aminoethyl)-1-Boc-piperidine is mainly obtained by reacting 4-piperidinmethanol with Boc acid (tert-butoxycarbonyl acid) under base catalysis. The specific synthetic route requires some knowledge and skills of organic synthesis reactions.
Regarding safety information, you need to pay attention to the following points:
1. 4-(2-Aminoethyl)-1-Boc-piperidine is an organic compound. It should be operated in a well-ventilated place to avoid inhaling its vapor or dust.
2. During operation, appropriate personal protective equipment should be worn, such as gloves, protective glasses and laboratory coats.
3. 4-(2-Aminoethyl)-1-Boc-piperidine should be kept away from flammable substances and strong oxidants, and stored in a closed container to prevent reaction with oxygen in the air.
Last Update:2024-04-09 19:05:46