1-N-Cbz-4-Methoxycarbonylmethyl-piperidine
1-N-Cbz-4-Methoxycarbonylmethyl-piperidine
CAS: 170737-53-8
Molecular Formula: C16H21NO4
1-N-Cbz-4-Methoxycarbonylmethyl-piperidine - Names and Identifiers
1-N-Cbz-4-Methoxycarbonylmethyl-piperidine - Physico-chemical Properties
| Molecular Formula | C16H21NO4 |
| Molar Mass | 291.34 |
| Density | 1.149±0.06 g/cm3(Predicted) |
| Boling Point | 402.9±28.0 °C(Predicted) |
| pKa | -1.93±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
1-N-Cbz-4-Methoxycarbonylmethyl-piperidine - Introduction
It is an organic compound with the chemical formula C18H21NO3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
It is a colorless to light yellow liquid with a special smell. It is soluble in organic solvents such as methylene chloride and ethanol at normal temperature, but insoluble in water. The melting point of this compound is 59-61 degrees Celsius.
Use:
is an important organic synthesis intermediates. It is often used to synthesize compounds such as drugs, pesticides, and specific functional molecules. For example, it can be used in the synthesis of drugs containing piperidine structures, such as anti-epileptic drugs Parkinson's disease drugs.
Method: The preparation of
is usually done through a two-step reaction. First, 4-piperidineethanol is reacted with Di (tert-butoxycarbonyl) methylnickel bromide to produce methyl N-di (tert-butoxycarbonyl) methyl-4-piperidineacetate. It is then reacted with chloroformate to produce the final calcium carbonate.
Safety Information:
It is an intermediate compound in organic synthesis, so proper safety measures need to be taken during operation. It may be irritating to the eyes and skin, so wear appropriate protective equipment when using it. In addition, it may also be toxic, and inhalation of its vapor or contact with its solution should be avoided. During use and storage, the relevant safety procedures shall be observed.
Nature:
It is a colorless to light yellow liquid with a special smell. It is soluble in organic solvents such as methylene chloride and ethanol at normal temperature, but insoluble in water. The melting point of this compound is 59-61 degrees Celsius.
Use:
is an important organic synthesis intermediates. It is often used to synthesize compounds such as drugs, pesticides, and specific functional molecules. For example, it can be used in the synthesis of drugs containing piperidine structures, such as anti-epileptic drugs Parkinson's disease drugs.
Method: The preparation of
is usually done through a two-step reaction. First, 4-piperidineethanol is reacted with Di (tert-butoxycarbonyl) methylnickel bromide to produce methyl N-di (tert-butoxycarbonyl) methyl-4-piperidineacetate. It is then reacted with chloroformate to produce the final calcium carbonate.
Safety Information:
It is an intermediate compound in organic synthesis, so proper safety measures need to be taken during operation. It may be irritating to the eyes and skin, so wear appropriate protective equipment when using it. In addition, it may also be toxic, and inhalation of its vapor or contact with its solution should be avoided. During use and storage, the relevant safety procedures shall be observed.
Last Update：2024-04-09 21:01:54
