1-O-Hexyl-2,3,5-trimethylhydroquinone
1-O-Hexyl-2,3,5-trimethylhydroquinone
CAS: 148081-72-5
Molecular Formula: C15H24O2
1-O-Hexyl-2,3,5-trimethylhydroquinone - Names and Identifiers
1-O-Hexyl-2,3,5-trimethylhydroquinone - Physico-chemical Properties
| Molecular Formula | C15H24O2 |
| Molar Mass | 236.35 |
| Density | 0.971±0.06 g/cm3(Predicted) |
| Melting Point | 72.5-73°C |
| Boling Point | 357.8±37.0 °C(Predicted) |
| Appearance | powder to crystal |
| Color | White to Light yellow to Dark green |
| pKa | 11.22±0.30(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
1-O-Hexyl-2,3,5-trimethylhydroquinone - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.195 ml | 20.976 ml | 41.952 ml |
| 5 mM | 0.839 ml | 4.195 ml | 8.39 ml |
| 10 mM | 0.42 ml | 2.098 ml | 4.195 ml |
| 5 mM | 0.084 ml | 0.42 ml | 0.839 ml |
Last Update：2024-01-02 23:10:35
1-O-Hexyl-2,3,5-trimethylhydroquinone - Reference Information
| biological activity | HTHQ (1-O-hexyl-2,3, 5-trimethhylhydrotron) is a potent lipophilic phenolic antioxidant. HTHQ has a strong antioxidant activity by reacting directly with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals. |
| Target | ROS |
| Cell Line: | PC12 cells PC12 cells |
| Concentration: | 0 μM, 1 μM, 10 μM, and 100 μM 10 μM |
| Incubation Time: | 24 hours 0.6-24 hours |
| Result: | Reduced cell viability at 24 hours caused by both 100 and 200 µM L-DOPA was significantly attenuated. Inhibited L-DOPA-induced phosphorylation of sustained extracellular signal-regulated kinases (ERK1/2), p38 mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK1/2). And also normalized L-DOPA-reduced Bcl-2-associated death protein (Bad) phosphorylation and Bcl-2-associated X protein (Bax) expression. Improved against DMN-induced liver fibrosis in male SD rats. |
| Animal Model: | 48 specific pathogen-free male Sprague Dawley (SD) rats (6-week-old ) with dimethylnitrosamine (DMN) |
| Dosage: | 50 mg/kg, 100 mg/kg, 200 mg/kg |
| Administration: | Oral administration; for 4 weeks |
Last Update：2024-04-09 15:16:56
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Product Name: 1-O-Hexyl-2,3,5-trimethylhydroquinone Visit Supplier Webpage Request for quotationCAS: 148081-72-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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