1-PYRIDIN-3-YL-PROPAN-2-ONE
1-(pyridin-3-yl)propan-2-one
CAS: 6302-03-0
Molecular Formula: C8H9NO
1-PYRIDIN-3-YL-PROPAN-2-ONE - Names and Identifiers
1-PYRIDIN-3-YL-PROPAN-2-ONE - Physico-chemical Properties
| Molecular Formula | C8H9NO |
| Molar Mass | 135.16 |
| Density | 1.064 g/cm3 |
| Melting Point | 110-115 °C |
| Boling Point | 80-81 °C(Press: 1 Torr) |
| Flash Point | 98.9°C |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate |
| Vapor Presure | 0.0647mmHg at 25°C |
| Appearance | Oil |
| Color | Yellow |
| pKa | 4.66±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.509 |
1-PYRIDIN-3-YL-PROPAN-2-ONE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
1-PYRIDIN-3-YL-PROPAN-2-ONE - Introduction
1-(pyridin-3-yl)propan-2-one is an organic compound with a chemical formula of C10H11NO and a molecular weight of 161.20g/mol.
Nature:
1-(pyridin-3-yl)propan-2-one is a colorless liquid with a characteristic aroma of pyridine. It is soluble in most organic solvents, such as ethanol, diethyl ether and dimethylformamide.
Use:
1-(pyridin-3-yl)propan-2-one are widely used in organic synthesis reactions. It can be used as an important intermediate for the preparation of various organic compounds, such as drugs, dyes and pesticides. The organic synthesis reaction includes the synthesis of carbonyl compounds, dehydrogenation reaction, cyclization reaction and nucleophilic substitution.
Preparation Method:
A method for synthesizing 1-(pyridin-3-yl)propan-2-one is to react 3-pyridinecarboxamide with ethyl acetate under basic conditions. First, 3-pyridinecarboxamide and ethyl acetate were added to a sodium sulfate acetate buffer, and then the reaction was carried out at room temperature. After the completion of the reaction, the pure 1-(pyridin-3-yl)propan-2-one product is obtained through the process steps of distillation and crystallization.
Safety Information:
1-(pyridin-3-yl)propan-2-one are organic compounds and should be handled with care. It is irritating and toxic, avoid contact with skin and eyes. During use, follow appropriate laboratory procedures and wear appropriate protective equipment, such as gloves, safety glasses and face shields. When handling the compound, maintain a well-ventilated laboratory environment and avoid breathing its vapors. If there is an accident, please seek the help of a doctor.
Nature:
1-(pyridin-3-yl)propan-2-one is a colorless liquid with a characteristic aroma of pyridine. It is soluble in most organic solvents, such as ethanol, diethyl ether and dimethylformamide.
Use:
1-(pyridin-3-yl)propan-2-one are widely used in organic synthesis reactions. It can be used as an important intermediate for the preparation of various organic compounds, such as drugs, dyes and pesticides. The organic synthesis reaction includes the synthesis of carbonyl compounds, dehydrogenation reaction, cyclization reaction and nucleophilic substitution.
Preparation Method:
A method for synthesizing 1-(pyridin-3-yl)propan-2-one is to react 3-pyridinecarboxamide with ethyl acetate under basic conditions. First, 3-pyridinecarboxamide and ethyl acetate were added to a sodium sulfate acetate buffer, and then the reaction was carried out at room temperature. After the completion of the reaction, the pure 1-(pyridin-3-yl)propan-2-one product is obtained through the process steps of distillation and crystallization.
Safety Information:
1-(pyridin-3-yl)propan-2-one are organic compounds and should be handled with care. It is irritating and toxic, avoid contact with skin and eyes. During use, follow appropriate laboratory procedures and wear appropriate protective equipment, such as gloves, safety glasses and face shields. When handling the compound, maintain a well-ventilated laboratory environment and avoid breathing its vapors. If there is an accident, please seek the help of a doctor.
Last Update：2024-04-09 21:01:54
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CAS: 6302-03-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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