1-PYRIDIN-4-YL-PIPERAZINE - Names and Identifiers
1-PYRIDIN-4-YL-PIPERAZINE - Physico-chemical Properties
Molecular Formula | C9H13N3
|
Molar Mass | 163.22 |
Density | 1.081±0.06 g/cm3(Predicted) |
Melting Point | 137-141 °C |
Boling Point | 195-200°C 0,3mm |
Flash Point | 195-200°C/0.3mm |
Water Solubility | Soluble in water. |
Solubility | soluble in Methanol |
Appearance | Crystalline powder |
Color | White to Light yellow |
BRN | 609705 |
pKa | 10.73±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Sensitive | Air Sensitive |
Refractive Index | 1.576 |
MDL | MFCD00040745 |
1-PYRIDIN-4-YL-PIPERAZINE - Risk and Safety
Risk Codes | R34 - Causes burns
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 - Wear suitable protective clothing.
S37/38/39 -
|
UN IDs | UN 3259 8/PG 2 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-34 |
HS Code | 29335990 |
Hazard Note | Irritant |
Hazard Class | 8 |
Packing Group | II |
1-PYRIDIN-4-YL-PIPERAZINE - Introduction
1-(4-Pyridine) piperazine, also known as 4-piperazinylpyridine, is an organic compound.
Nature:
1-(4-Pyridine) piperazine is a white crystalline solid with weak basic properties. It is insoluble in water at room temperature, but soluble in organic solvents such as ethanol and dimethyl sulfoxide. Its molecular formula is C11H14N2 and its molecular weight is 174.24g/mol.
Use:
1-(4-Pyridine) piperazine has important applications in the field of medicine. It can be used as a pharmaceutical intermediate for the synthesis of a variety of bioactive compounds, such as antihypertensive drugs, antidepressants and antitumor drugs. In addition, it can also be used as a catalyst in organic synthesis.
Preparation Method:
1-(4-Pyridine) piperazine is usually prepared by nucleophilic substitution reaction of pyridine and 1,4-dibromobutane under basic conditions. During the preparation process, attention should be paid to safe operation, avoid contact with skin and inhalation of gas.
Safety Information:
1-(4-pyridine) piperazine is generally safe under normal use conditions, but the following safety precautions should be paid attention to during preparation and operation:
-Avoid inhaling dust or vapors and wear suitable protective masks and glasses.
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical advice.
-Follow laboratory safety regulations during operation, use appropriate protective gloves and laboratory ventilation equipment.
-When storing and transporting, it should be stored in a sealed container, away from fire and oxidizing agents.
The information provided above is for reference only. Please read the relevant literature and safety materials carefully before specific use, and follow the correct experimental operation procedures and safety measures.
Last Update:2024-04-09 20:52:54