1-Palmitoyl-N-hydroxysuccinimide - Names and Identifiers
1-Palmitoyl-N-hydroxysuccinimide - Physico-chemical Properties
Molecular Formula | C20H35NO4
|
Molar Mass | 353.5 |
Density | 1.03±0.1 g/cm3(Predicted) |
Melting Point | 81°C |
Boling Point | 447.1±28.0 °C(Predicted) |
Flash Point | 224.2°C |
Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
Vapor Presure | 3.45E-08mmHg at 25°C |
Appearance | Colorless and glossy sheet |
Color | White to Off-White |
BRN | 1547411 |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Stability | Moisture Sensitive; Store in Freezer |
Refractive Index | 1.488 |
1-Palmitoyl-N-hydroxysuccinimide - Risk and Safety
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
1-Palmitoyl-N-hydroxysuccinimide - Reference
Reference Show more | 1. [IF=10.317] Ting Gong et al."Palmitic acid-modified bovine serum albumin nanoparticles target scavenger receptor-A on activated macrophages to treat rheumatoid arthritis."Biomaterials. 2020 Nov;258:120296 |
1-Palmitoyl-N-hydroxysuccinimide - Introduction
N-succinimidyl palmitate(Palmitic acid N-hydroxysuccinimide ester) is a compound with the chemical structure C16H31CONHSO2CH2CO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: brownish-orange to light yellow solid.
-Solubility: Soluble in some organic solvents, such as chloroform, ether, methanol, etc.
-Melting point: About 30-50 ° C.
-Stability: Stable to acid, alkali and heat.
Use:
-Biochemical Research: N-succinimidyl palmitate is often used as an active compound and plays an important role in the modification of biologically active molecules.
-Chemical synthesis: As an activator, it can be used in esterification, etherification, amidation and other reactions to promote the reaction.
-Drug development: In drug synthesis, the compound can be used as an activator or intermediate to help synthesize compounds with specific biological activities.
-Surfactant: In some applications, N-succinimidyl palmitate can be used as a surfactant, which has the ability to form micelles.
Method:
The synthesis of N-succinimidyl palmitate can be obtained by the reaction of palmitic acid with hydroxysuccinimide. In the reaction, the two are reacted in a molar ratio of 1:1, and the reaction is carried out in a suitable solvent at a suitable temperature to produce the target product.
Safety Information:
- N-succinimidyl palmitate is irritating and contact with the skin may cause irritation or allergic reactions. During use, wear appropriate protective gloves and glasses to avoid skin and eye contact.
-During storage and transportation, avoid contact with harmful substances such as strong oxidants and strong acids.
-When using and handling, should follow the relevant safety operation procedures and regulations.
Please note that this is only a general introduction to the N-succinimidyl palmitate, and specific nature, use, formulation and safety information may require more detailed information and experimental requirements.
Last Update:2024-04-09 15:17:52