1-Phenyl-3-Hydroxy-1,2,4-triazole

1-Phenyl-3-Hydroxy-1,2,4-triazole - Names and Identifiers

Name	1-Phenyl-3-Hydroxy-1,2,4-triazole
Synonyms	224-187-5 1-PHENYL-1,2,4-TRIAZOL-3-OL 1-PHENYL-1H-1,2,4-TRIAZOL-3-OL 1-Phenyl-1H-1,2,4-triazol-3-ol 1-Phenyl-2H-1,2,4-triazol-3-one 1H-1,2,4-triazol-3-ol, 1-phenyl- 3-Hydroxy-1-Phenyl-1,2,4-Triazole 1-PHENYL-3-HYDROXY-1,2,4-TRIAZOLE 1-Phenyl-3-Hydroxy-1,2,4-triazole 3-Hydroxy-1-phenyl-1,2,4-triazole 3-Hydroxy-1-Phenyl-1H-1,2,4-Triazole 1-Phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one 1,2-dihydro-1-phenyl-3H-1,2,4-triazol-3-one
CAS	4231-68-9
EINECS	224-187-5
InChI	InChI=1/C8H7N3O/c12-8-9-6-11(10-8)7-4-2-1-3-5-7/h1-6H,(H,10,12)

1-Phenyl-3-Hydroxy-1,2,4-triazole - Physico-chemical Properties

Molecular Formula	C8H7N3O
Molar Mass	161.16
Density	1.32±0.1 g/cm3(Predicted)
Melting Point	277-280
Boling Point	392.2°C at 760 mmHg
Flash Point	191°C
Vapor Presure	1.03E-06mmHg at 25°C
Appearance	Crystallization
pKa	9.13±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.665
Physical and Chemical Properties	Oxazole alcohol industrial products are light yellow crystals, m.p.284 ~ 286 ℃, soluble in dimethylformamide, slightly soluble in water.
Use	Intermediate for triazophos pesticide

1-Phenyl-3-Hydroxy-1,2,4-triazole - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

1-Phenyl-3-Hydroxy-1,2,4-triazole - Reference Information

Use

1-phenyl-3-hydroxy-1, 2, 4-triazole, also known as benzazole alcohol, is an intermediate of the organophosphorus insecticide triazophos.
used for triazophos pesticide intermediate
used as pesticide triazophos intermediate

Production method

The preparation method is to react 1-phenylsemicarbazide with formic acid to obtain benzazole alcohol. 186kg 1-phenylsemicarbazide, 113kg of formic acid, 20kg of catalyst and 30L of water are added into a 1000L reaction kettle, stirred evenly, heated to 100 ℃, refluxed for 6h, then 400L of water is added, cooled to 20 ℃, filtered, the filter cake is washed with 2% NaHCO3 and water to be neutral, dried to obtain light yellow crystal, namely benzazole alcohol. Phenylhydrazine, urea and formic acid can also be used as raw materials to obtain benzazole alcohol through condensation and cyclition reactions.

Last Update：2024-04-09 21:54:55