1-bromo-4-(methylsulphonyl)benzene
4-Bromophenyl methyl sulfone
CAS: 3466-32-8
Molecular Formula: C7H7BrO2S
1-bromo-4-(methylsulphonyl)benzene - Names and Identifiers
1-bromo-4-(methylsulphonyl)benzene - Physico-chemical Properties
| Molecular Formula | C7H7BrO2S |
| Molar Mass | 235.1 |
| Density | 1.595±0.06 g/cm3(Predicted) |
| Melting Point | 103-107 °C (lit.) |
| Boling Point | 348.6±34.0 °C(Predicted) |
| Flash Point | 164.6°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.0001mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White |
| BRN | 2045675 |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.563 |
| MDL | MFCD00025065 |
| Physical and Chemical Properties | Melting point 103-107°C(lit.) BRN 2045675 |
1-bromo-4-(methylsulphonyl)benzene - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29309090 |
| Hazard Note | Irritant |
1-bromo-4-(methylsulphonyl)benzene - Introduction
4-Bromophene methyl sulfone, chemical formula C7H7BrO2S, is an organic compound. Its properties are as follows:
1. Appearance: 4-Bromophenyl methyl sulfone is a white crystalline solid or powder.
2. melting point: about 60-62 ℃.
3. Boiling point: about 275-280 ℃.
4. Solubility: 4-Bromophene methyl sulfone is soluble in organic solvents such as ethanol, acetone and dichloromethane.
The main uses of 4-Bromophenyl methyl sulfone are as follows:
1. synthetic drugs: 4-Bromophenyl methyl sulfone can be used as drug intermediates for the synthesis of various drugs.
2. Organic synthesis: It is widely used in organic synthesis reactions, such as being used as a substrate for Grignard reactions, or reducing aryl sulfates.
3. Chemical reagent: It can be used as a reagent in organic synthesis, for example, as a substitute for bromosulfonic acid.
The method for preparing 4-Bromophenyl methyl sulfone is as follows:
1. The phenyl methyl sulfone is reacted with bromide under alkaline conditions to obtain 4-Bromophenyl methyl sulfone.
2. phenylsulfonyl bromide reacts with methanol, and then 4-Bromophenyl methyl sulfone is obtained by reduction.
As for safety information, please note the following:
1. 4-Bromophenyl methyl sulfone should avoid direct contact with skin and eyes during use. In case of accidental contact, rinse immediately with plenty of water.
2. Appropriate personal protective equipment, such as laboratory gloves and eye protection, should be used during operation.
3. in storage and handling, should be away from the fire and high temperature, maintain a well-ventilated environment.
4. 4-Bromophenyl methyl sulfone is a potential organic intermediate. Users should pay attention to its toxicity and chemical stability during operation and storage.
1. Appearance: 4-Bromophenyl methyl sulfone is a white crystalline solid or powder.
2. melting point: about 60-62 ℃.
3. Boiling point: about 275-280 ℃.
4. Solubility: 4-Bromophene methyl sulfone is soluble in organic solvents such as ethanol, acetone and dichloromethane.
The main uses of 4-Bromophenyl methyl sulfone are as follows:
1. synthetic drugs: 4-Bromophenyl methyl sulfone can be used as drug intermediates for the synthesis of various drugs.
2. Organic synthesis: It is widely used in organic synthesis reactions, such as being used as a substrate for Grignard reactions, or reducing aryl sulfates.
3. Chemical reagent: It can be used as a reagent in organic synthesis, for example, as a substitute for bromosulfonic acid.
The method for preparing 4-Bromophenyl methyl sulfone is as follows:
1. The phenyl methyl sulfone is reacted with bromide under alkaline conditions to obtain 4-Bromophenyl methyl sulfone.
2. phenylsulfonyl bromide reacts with methanol, and then 4-Bromophenyl methyl sulfone is obtained by reduction.
As for safety information, please note the following:
1. 4-Bromophenyl methyl sulfone should avoid direct contact with skin and eyes during use. In case of accidental contact, rinse immediately with plenty of water.
2. Appropriate personal protective equipment, such as laboratory gloves and eye protection, should be used during operation.
3. in storage and handling, should be away from the fire and high temperature, maintain a well-ventilated environment.
4. 4-Bromophenyl methyl sulfone is a potential organic intermediate. Users should pay attention to its toxicity and chemical stability during operation and storage.
Last Update：2024-04-09 18:58:34
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Product Name: 4-Bromophenyl methyl sulfone Visit Supplier Webpage Request for quotationCAS: 3466-32-8
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