1-chloro-2-methanidylbenzene,chlorozinc(1+)
2-Chlorobenzylzinc chloride
CAS: 312624-11-6
Molecular Formula: C7H6Cl2Zn
1-chloro-2-methanidylbenzene,chlorozinc(1+) - Names and Identifiers
1-chloro-2-methanidylbenzene,chlorozinc(1+) - Physico-chemical Properties
| Molecular Formula | C7H6Cl2Zn |
| Molar Mass | 226.42 |
| Density | 0.975g/mLat 25°C |
| Flash Point | 1°F |
| Storage Condition | 2-8°C |
1-chloro-2-methanidylbenzene,chlorozinc(1+) - Risk and Safety
| Risk Codes | R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | 1 |
1-chloro-2-methanidylbenzene,chlorozinc(1+) - Introduction
2-Chlorobenzylzinc chloride is an organic zinc compound with the chemical formula C7H6Cl2Zn. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Chlorobenzylzinc is chloride as a colorless or pale yellow liquid.
-Density: Approximately 1.28 g/mL.
-Melting point: approximately -15°C.
-Boiling point: about 173°C.
-Solubility: It is soluble in common organic solvents such as ethanol and dimethylformamide.
Use:
- 2-Chlorobenzylzinc chloride can be used as an important reagent in organic synthesis, and is commonly used in the functional reactions of aromatic hydrocarbons, such as nucleophilic substitution and coupling reactions of aromatic hydrocarbons.
-It is also commonly used in C- C bond formation reactions in organic synthesis, such as using this reagent for Carbocupration reactions.
Preparation Method:
The preparation of 2-Chlorobenzylzinc chloride is generally carried out by the following steps:
1. first mix 2-chloromethylbenzene with zinc powder;
2. adding cuprous chloride as a catalyst and continuing to stir the reaction mixture;
3. under appropriate conditions, the reaction of zinc powder and 2-chloromethylbenzene reaction, 2-Chlorobenzylzinc chloride.
Safety Information:
- 2-Chlorobenzylzinc chloride is a toxic compound and care should be taken to avoid contact with skin, eyes and inhalation of its vapors.
-During use and storage, appropriate safety measures should be taken, such as wearing protective gloves, protective glasses and masks.
-If you come into contact with 2-Chlorobenzylzine chloride, immediately rinse the affected area with plenty of water and seek medical attention immediately.
Nature:
-Appearance: 2-Chlorobenzylzinc is chloride as a colorless or pale yellow liquid.
-Density: Approximately 1.28 g/mL.
-Melting point: approximately -15°C.
-Boiling point: about 173°C.
-Solubility: It is soluble in common organic solvents such as ethanol and dimethylformamide.
Use:
- 2-Chlorobenzylzinc chloride can be used as an important reagent in organic synthesis, and is commonly used in the functional reactions of aromatic hydrocarbons, such as nucleophilic substitution and coupling reactions of aromatic hydrocarbons.
-It is also commonly used in C- C bond formation reactions in organic synthesis, such as using this reagent for Carbocupration reactions.
Preparation Method:
The preparation of 2-Chlorobenzylzinc chloride is generally carried out by the following steps:
1. first mix 2-chloromethylbenzene with zinc powder;
2. adding cuprous chloride as a catalyst and continuing to stir the reaction mixture;
3. under appropriate conditions, the reaction of zinc powder and 2-chloromethylbenzene reaction, 2-Chlorobenzylzinc chloride.
Safety Information:
- 2-Chlorobenzylzinc chloride is a toxic compound and care should be taken to avoid contact with skin, eyes and inhalation of its vapors.
-During use and storage, appropriate safety measures should be taken, such as wearing protective gloves, protective glasses and masks.
-If you come into contact with 2-Chlorobenzylzine chloride, immediately rinse the affected area with plenty of water and seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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