1-chloro-2-nitrobenzene
1-Chloro-2-nitrobenzene
CAS: 88-73-3
Molecular Formula: C6H4ClNO2
1-chloro-2-nitrobenzene - Names and Identifiers
1-chloro-2-nitrobenzene - Physico-chemical Properties
| Molecular Formula | C6H4ClNO2 |
| Molar Mass | 157.55 |
| Density | 1.348 g/mL at 25 °C (lit.) |
| Melting Point | 31-33 °C (lit.) |
| Boling Point | 246 °C (lit.) |
| Flash Point | >230°F |
| Water Solubility | 0.43 g/L (20 ºC) |
| Solubility | alcohol: soluble |
| Vapor Presure | 0.04 mm Hg ( 25 °C) |
| Vapor Density | 5.4 (vs air) |
| Appearance | Fused Crystalline Mass |
| Color | Yellow |
| Merck | 14,2151 |
| BRN | 509273 |
| PH | 6 (0.4g/l, H2O, 20℃) |
| Storage Condition | Store below +30°C. |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, strong bases, alkali metals. |
| Explosive Limit | 1.15-13.1%(V) |
| Refractive Index | 1.5520 (estimate) |
| Physical and Chemical Properties | trait light yellow monoclinic needle crystal. |
| Use | It is an important intermediate of pesticides (such as carbendazim), dyes and medicines, and can also be used as the raw material of rubber accelerator m |
1-chloro-2-nitrobenzene - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R22 - Harmful if swallowed R24 - Toxic in contact with skin R52 - Harmful to aquatic organisms R53 - May cause long-term adverse effects in the aquatic environment R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S28A - |
| UN IDs | UN 1578 6.1/PG 2 |
| WGK Germany | 2 |
| RTECS | CZ0875000 |
| TSCA | Yes |
| HS Code | 29049085 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | II |
1-chloro-2-nitrobenzene - Upstream Downstream Industry
1-chloro-2-nitrobenzene - Nature
Open Data Verified Data
light yellow monoclinic needle crystal. Flammable. The relative density was 1. 368. Melting point 32.5 °c. Boiling point 245.5 °c. Decomposition began at 283 °c. Flash point 127 °c. Slightly soluble in water, 20 ° C water dissolved 0. 03%. Soluble in ethanol, ether, acetone, benzene and other organic solvents.
Last Update：2024-01-02 23:10:35
1-chloro-2-nitrobenzene - Preparation Method
Open Data Verified Data
Same as p-nitrochlorobenzene.
Last Update：2022-01-01 10:44:40
1-chloro-2-nitrobenzene - Use
Open Data Verified Data
pesticides (such as carbendazim), dyes, important intermediates of medicine, can also be used as raw materials of rubber Auxiliary Agent M.
Last Update：2022-01-01 10:44:40
1-chloro-2-nitrobenzene - Safety
Open Data Verified Data
see p-nitrochlorobenzene for toxicity and protection. See p-nitrochlorobenzene for packaging, storage and transportation of this product.
Last Update：2022-01-01 10:44:41
1-chloro-2-nitrobenzene - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| (IARC) carcinogen classification | 2B (Vol. 65, 123) 2020 |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| uses | is an important intermediate of pesticides (such as carbendazim), dyes, medicines, it can also be used as the raw material of rubber accelerator M. O-nitrochlorobenzene is an important intermediate in organic synthesis and can be derived from a variety of intermediates. In the dye industry for the production of yellow GC, orange GR, etc.; In the auxiliary for the production of rubber accelerator M and DM, etc.; In the perfume industry for the synthesis of vanillin; the pesticide industry is used to produce thiophanate and thiophanate-methyl, carbendazim; It is also a raw material for the benzotriazole ultraviolet absorber. It is also an important intermediate of medicine. for organic synthesis |
| production method | mixed nitrochlorobenzene was obtained by nitration of chlorobenzene with mixed acid. The contents of the three isomers were roughly as follows: P-nitrochlorobenzene accounted for 65%, O-nitrochlorobenzene accounted for 30%, and M-nitrochlorobenzene accounted for 1%. The process is as follows: first, the prepared mixed acid (containing 30% nitric acid, 56% sulfuric acid, and 14% water) is added into the nitrifying pot. The temperature was maintained at 40-55 °c, Chlorobenzene was slowly added, and the temperature was increased to 80 °c, and the reaction was stirred for 2H. The mixture of nitrochlorobenzene in the upper layer was washed with water and alkali. After washing with water, the mixture was separated by standing and dried at 100 ° C. Under vacuum to obtain mixed nitrochlorobenzene. Then in the crystallizer, the above-mentioned dried mixed nitrochlorobenzene is gradually cooled to 15 ° C. That is, a large amount of P-nitrochlorobenzene is accumulated in the pipe wall, and is heated and melted, brought into the storage tank, and subjected to vacuum distillation, P-nitrochlorobenzene was obtained after chlorobenzene removal. The mother liquor discharged from the lower part of the crystallizer contains about 35% of p-nitrochlorobenzene, 64% of O-nitrochlorobenzene and a small amount of M-nitrochlorobenzene for further separation. The crude O-nitrochlorobenzene, which is separated by distillation, is placed in the crystallizer, The use of reducing the temperature in the mold to 15 degrees Celsius to make the crystallization of the way, that is, to get the finished product. Raw material consumption quota: P-nitrochlorobenzene, chlorobenzene 1150kg/t, nitric acid 672kg/t, sulfuric acid (92.5%)632kg/t. |
| category | toxic substances |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50: 268 mg/kg; Oral-mouse LD50: 135 mg/kg |
| flammability hazard characteristics | open flame flammable; High heat emissions toxic chloride, nitrogen oxide gas |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored separately from oxidants and food additives |
| fire extinguishing agent | water, foam, carbon dioxide, sand |
| Occupational Standard | TWA 1 mg/m3; Tel 2 mg/m3 |
| spontaneous combustion temperature | 500 ° F. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 02:00:12
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Raw Materials for 1-chloro-2-nitrobenzene
Downstream Products for 1-chloro-2-nitrobenzene
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