1-isopropyl-1H-pyrazol-4-amine

1-isopropyl-1H-pyrazol-4-amine - Names and Identifiers

Name	4-AMINO-1-ISOPROPYL-1H-PYRAZOLE
Synonyms	1-ISOPROPYLPYRAZOL-4-AMINE 4-Amino-1-(iso-propyl)pyrazole 1-isopropyl-1H-pyrazol-4-amine 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE 4-AMINO-1-ISOPROPYL-1H-PYRAZOLE HCL 1-isopropyl-1H-pyrazol-4-amine 1HCl 1-(1-methylethyl)-1H-pyrazol-4-amine
CAS	97421-16-4

1-isopropyl-1H-pyrazol-4-amine - Physico-chemical Properties

Molecular Formula	C6H11N3
Molar Mass	125.17
Density	1.12±0.1 g/cm3(Predicted)
Boling Point	234.2±13.0 °C(Predicted)
pKa	3.74±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

1-isopropyl-1H-pyrazol-4-amine - Introduction

It is an organic compound with the chemical formula C6H10N2. It is a colorless to slightly yellow solid. The following is a description of the properties, uses, methods of manufacture and safety information:

Nature:
1. Appearance: colorless to yellowish solid.
2. Solubility: Soluble in some organic solvents, such as ethanol, dimethylformamide and dimethyl sulfoxide.
3. Melting Point: about 80-82 ℃.

Use:
As an organic synthesis reagent, it has a wide range of applications in the field of drug synthesis, Pesticide Synthesis, chemical synthesis and so on.
1. Drug synthesis: as a drug intermediate, commonly used in the synthesis of anti-epileptic drugs, anti-anxiety drugs.
2. Pesticide Synthesis: for the synthesis of some pesticides and herbicides.
3. Chemical Synthesis: can be used for the synthesis of various chemicals, such as dyes, polymer materials.

Method:
There are two main preparation methods:
1. By the reaction of Barr-stearamide: Barr-stearamide is first reacted with isopropylamine to give 4-amido-1-isopropyl-1h-pyrazole, the 4-amido group is then removed by a hydrogenolysis reaction to give the target product.
2. Through etherification reaction: 4-keto-1-isopropyl-1H-pyrazole is reacted with an etherification reagent (such as methyl bromide) to obtain the target product.

Safety Information:
1. Is irritating and corrosive, please pay attention to personal protective measures, such as wearing protective gloves, goggles, etc.
2. Use should avoid contact with skin, eyes and respiratory tract, and ensure that the operation in a well ventilated place.
3. In case of contact, rinse immediately with plenty of water and seek medical treatment.
4. Avoid contact with oxidants, acids, alkalis and other substances during storage and transportation.

Last Update：2024-04-09 15:18:03