1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole
1-Methylindazole-5-boronic acid pinacol ester
CAS: 1235469-00-7
Molecular Formula: C14H19BN2O2
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Names and Identifiers
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Physico-chemical Properties
| Molecular Formula | C14H19BN2O2 |
| Molar Mass | 258.12 |
| Density | 1.11±0.1 g/cm3(Predicted) |
| Boling Point | 385.0±15.0 °C(Predicted) |
| pKa | 1.51±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD15071438 |
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Introduction
1-Methylindazole-5-boronic acid pinacol ester is an organic compound with the chemical formula C15H22BN2O2. It is solid and has a white to white-like color. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to white-like solid
-Solubility: Soluble in organic solvents such as dichloromethane and ether, insoluble in water
-Melting point: about 110-115 degrees Celsius
-Stability: stable under normal temperature and pressure
Use:
1-Methylindazole-5-boronic acid pinacol ester is an organic boron compound, which has important application value in organic synthesis. It is often used as a precursor of a complex and can form a complex by combining with a metal complex ion. These complexes can be used in catalytic reactions and cross-coupling reactions in organic synthesis, such as Suzuki coupling reactions.
Preparation Method:
1-Methylindazole-5-boronic acid pinacol ester is generally synthesized from an appropriate starting material by chemical reaction. A common synthetic approach is to react the appropriate starting material with sodium borate and tetramethylammonium iodide to give the desired product using a nucleophilic substitution reaction. Care needs to be taken to use appropriate chemical manipulations and control conditions during the synthesis.
Safety Information:
1-Methylindazole-5-boronic acid pinacol ester has limited safety information, so it is necessary to take appropriate safety measures during handling and handling, such as wearing appropriate protective equipment (gloves, glasses, lab clothes, etc.). At the same time, it needs to be stored in a dry, cool place and avoid contact with strong oxidants. When using or handling this compound, it is best to follow relevant safety practices and laboratory guidelines, and dispose of waste properly.
Nature:
-Appearance: White to white-like solid
-Solubility: Soluble in organic solvents such as dichloromethane and ether, insoluble in water
-Melting point: about 110-115 degrees Celsius
-Stability: stable under normal temperature and pressure
Use:
1-Methylindazole-5-boronic acid pinacol ester is an organic boron compound, which has important application value in organic synthesis. It is often used as a precursor of a complex and can form a complex by combining with a metal complex ion. These complexes can be used in catalytic reactions and cross-coupling reactions in organic synthesis, such as Suzuki coupling reactions.
Preparation Method:
1-Methylindazole-5-boronic acid pinacol ester is generally synthesized from an appropriate starting material by chemical reaction. A common synthetic approach is to react the appropriate starting material with sodium borate and tetramethylammonium iodide to give the desired product using a nucleophilic substitution reaction. Care needs to be taken to use appropriate chemical manipulations and control conditions during the synthesis.
Safety Information:
1-Methylindazole-5-boronic acid pinacol ester has limited safety information, so it is necessary to take appropriate safety measures during handling and handling, such as wearing appropriate protective equipment (gloves, glasses, lab clothes, etc.). At the same time, it needs to be stored in a dry, cool place and avoid contact with strong oxidants. When using or handling this compound, it is best to follow relevant safety practices and laboratory guidelines, and dispose of waste properly.
Last Update：2024-04-10 22:29:15
