1-methylazepan-2-one
N-Methylcaprolactam
CAS: 2556-73-2
Molecular Formula: C7H13NO
1-methylazepan-2-one - Names and Identifiers
1-methylazepan-2-one - Physico-chemical Properties
| Molecular Formula | C7H13NO |
| Molar Mass | 127.18 |
| Density | 0.991 g/mL at 25 °C (lit.) |
| Boling Point | 106-108 °C/6 mmHg (lit.) |
| Flash Point | 218°F |
| Water Solubility | Fully miscible with water. |
| Solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly) |
| Vapor Presure | 0.0252mmHg at 25°C |
| Appearance | Oil |
| Specific Gravity | 0.991 |
| Color | Colourless |
| Merck | 14,5989 |
| pKa | -0.41±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Hygroscopic |
| Refractive Index | n20/D 1.484(lit.) |
| Physical and Chemical Properties | The boiling point 106-108 ℃(0.8kPa), relative density 0.991, refractive index 1.4839, flash point 103 ℃. |
| Use | Used as a pharmaceutical Intermediate |
1-methylazepan-2-one - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R21/22 - Harmful in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| RTECS | CM4025000 |
| HS Code | 29337900 |
1-methylazepan-2-one - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | used as an intermediate and solvent for organic synthesis. Used as a pharmaceutical intermediate |
| Production method | It is obtained by the reaction of lactam and dimethyl sulfate. The caprolactam is dissolved in benzene, heated and refluxed, and dimethyl sulfate is added dropwise under stirring. After adding, reflux reaction for 16h, cooling, washing with 50% potassium carbonate solution, dividing the upper organic layer, drying with anhydrous calcium chloride overnight. After filtering out calcium chloride, benzene is distilled under normal pressure, and N-methyl caprolactam is collected by decompression distillation in drought. The yield was 68.8%. |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: N-Methylcaprolactam Request for quotationCAS: 2556-73-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: N-Methylcaprolactam Request for quotationCAS: 2556-73-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: N-Methylcaprolactam Request for quotation
CAS: 2556-73-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
CAS: 2556-73-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Spot supply
Product Name: N-Methylcaprolactam Request for quotationCAS: 2556-73-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: N-Methylcaprolactam Request for quotationCAS: 2556-73-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: N-Methylcaprolactam Request for quotation
CAS: 2556-73-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
CAS: 2556-73-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
View History