1-tert-Butyl-4-piperidone

1-tert-Butyl-4-piperidone - Names and Identifiers

Name	1-tert-butyl-4-piperidone
Synonyms	1-t-butylpiperidin4-one 1-tert-butyl-4-piperidone 1-tert-Butyl-4-piperidone 1-tert-butylpiperidin-4-one 1-tert-Butylpiperidine-4-one 1-TERT-BUTYL-PIPERIDIN-4-ONE 1-(1,1-Dimethylethyl)-4-piperidinone
CAS	1465-76-5
EINECS	215-982-8
InChI	InChI=1/C9H17NO/c1-9(2,3)10-6-4-8(11)5-7-10/h4-7H2,1-3H3

1-tert-Butyl-4-piperidone - Physico-chemical Properties

Molecular Formula	C9H17NO
Molar Mass	155.24
Density	0.968
Melting Point	92-94 °C (sublm)(Press: 10 Torr)
Boling Point	225℃
Flash Point	83℃
Vapor Presure	0.0883mmHg at 25°C
BRN	471469
pKa	8.26±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.472

1-tert-Butyl-4-piperidone - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3

1-tert-Butyl-4-piperidone - Introduction

1-tert-butyl-4-piperidone is an organic compound with the chemical formula C11H15NO.

Nature:
-Appearance: 1-tert-butyl-4-piperidone is white crystal or crystalline powder.
-Melting point: about 36-38 degrees Celsius.
-Boiling point: About 235 degrees Celsius.
-Density: about 0.996g/cm³.
-Solubility: Soluble in alcohol, ether and other organic solvents, slightly soluble in water.

Use:
1-tert-butyl-4-piperidone is mainly used in medicine as an anti-anxiety drug and a sedative. It can reduce anxiety and panic by regulating nervous system function and help improve sleep quality.

Method:
The preparation methods of 1-tert-butyl-4-piperidone are various. One of the common methods is to generate tert-butyl benzoate by the reaction of benzoic acid and tert-butyl magnesium bromide, and then through acid catalysis and dehydration The reaction converts the tert-butyl benzoate into 1-tert-butyl-4-piperidone.

Safety Information:
1-tert-butyl-4-piperidone is an organic compound, please follow the relevant safety procedures. It is irritating to the eyes, skin and respiratory system and should be exposed to wear appropriate personal protective equipment. Keep away from ignition and oxidizing agents during use or storage. Be careful to avoid inhalation or ingestion when handling, and keep away from children and pets. In the event of an accident, a doctor should be called immediately and information on chemicals should be provided.

Last Update：2024-04-09 02:00:42