1-tert-butyl-3-propan-2-ylthiourea

1-tert-butyl-3-propan-2-ylthiourea - Names and Identifiers

Name	N-T-Butyl-N'-Isopropylthiourea
Synonyms	N-T-BUTYL-N'-ISOPROP N-T-Butyl-N'-Isopropylthiourea N-T-BUTYL-N'-ISOPROPYLTHIOUREA 1-Isopropyl-3-Tert-Butylthiourea 1-tert-butyl-3-propan-2-ylthiourea 1-(tert-butyl)-3-isopropylthiourea 3-tert-butyl-1-(propan-2-yl)thiourea Thiourea, N-(1,1-dimethylethyl)-N'-(1-methylethyl)-
CAS	52599-24-3

1-tert-butyl-3-propan-2-ylthiourea - Physico-chemical Properties

Molecular Formula	C8H18N2S
Molar Mass	174.31
Density	0.949±0.06 g/cm3(Predicted)
Melting Point	150-152℃
Boling Point	215.3±23.0 °C(Predicted)
pKa	14.31±0.70(Predicted)
Storage Condition	Room Temprature
Physical and Chemical Properties	This product is pure white crystals, m.p.148.5 ~ 149.5 ℃, insoluble in benzene, toluene and other aromatic hydrocarbons, soluble in acetone, chloroform, dimethylformamide and other organic solvents.

1-tert-butyl-3-propan-2-ylthiourea - Reference Information

Uses

1-isopropyl-3-tert-butylthiourea is abbreviated as thiourea, which is an intermediate of the insecticide buprofezin.

Production method

The preparation method is the reaction of tert-butyl isothiocyanate and isopropylamine to form thiourea. Isopropylamine and toluene are vacuum pumped into the reaction kettle, and tert-butyl isothiocyanate is added dropwise by stirring at 10~25 ℃, the dropwise is finished within about 1~2h, the temperature is kept warm and stirred for 2~4h, the centrifuge is put into filtration after the reaction is finished, the filtrate is recovered and applied, and the filter cake is dried to obtain solid thiourea.

Last Update：2024-04-09 15:16:50