1-乙基-6,7,8-三氟-1,4-二氢-4-氧代喹啉-2-羧酸

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代喹啉-2-羧酸 - Names and Identifiers

Name	1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid
Synonyms	T66 BN EVJ B2 DVQ HF IF JF [WLN] 1-Ethy-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 1-Ethyl-6,7,8-Trifluoro-1,4-Digydro-4-Oxo-3-Quinolinecarboxylicacid 1-ETHYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLICACID 1,4-Dihydro-1-ethyl-4-oxo-6,7,8-trifluoro-3-quinolinecarboxylic acid 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 1-Ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid 1-Ethyl-4-oxo-6,7,8-trifluoro-1,4-dihydroquinoline-3-carboxylic acid 3-quinolinecarboxylic acid, 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-
CAS	75338-42-0
EINECS	616-213-2
InChI	InChI=1/C12H8F3NO3/c1-2-16-4-6(12(18)19)11(17)5-3-7(13)8(14)9(15)10(5)16/h3-4H,2H2,1H3,(H,18,19)

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代喹啉-2-羧酸 - Physico-chemical Properties

Molecular Formula	C12H8F3NO3
Molar Mass	271.19
Density	1.527±0.06 g/cm3(Predicted)
Melting Point	211-213 °C
Boling Point	401.7±45.0 °C(Predicted)
Flash Point	196.743°C
Vapor Presure	0mmHg at 25°C
Appearance	White crystal
pKa	-0?+-.0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.557

1-乙基-6,7,8-三氟-1,4-二氢-4-氧代喹啉-2-羧酸 - Introduction

1-Ethyl-6,7,8-trifluoro-1, is an organic compound with the chemical formula C13H9F3NO3.

Nature:
1-Ethyl-6,7,8-trifluoro-1, acid is a white solid with a special medicinal smell. It is stable at room temperature, but decomposes at high temperatures. The compound is soluble in organic solvents such as methylene chloride and dimethyl sulfoxide, and insoluble in water.

Use:
1-Ethyl-6,7,8-trifluoro-1, acid is mainly used in the field of medicine. It is an intermediate of quinolone antibiotics and can be used in the synthesis of other drugs, such as fluoroquinolones.

Preparation Method:
1-Ethyl-6,7,8-trifluoro-1, the synthesis of acid is generally carried out by chemical reaction. A common method is to react quinolinone with ethyl lithium, followed by fluorination and carboxylation to obtain the target product.

Safety Information:
1-Ethyl-6,7,8-trifluoro-1, acid should be stored in a sealed, dry environment, away from fire and oxidizing agents. Wear protective gloves and goggles during operation to avoid contact with skin and eyes. In case of careless contact, rinse with plenty of water immediately. In case of serious discomfort, seek medical treatment.

In addition, for the preparation and use of chemicals, please always refer to the relevant safety procedures and comply with relevant regulations and guidelines.

Last Update：2024-04-09 20:52:54