Name | 1-Aminocyclopropanecarboxylic acid |
Synonyms | 1-AMinocyclopropanecarbox... 1-AMino-1-carboxycyclopropane AMinocyclopropanecarboxylic acid 1-Aminocyclopropanecarboxylic acid 1-Amino-1-cyclopropanecarboxylic acid 1-Aminocyclopropane-1-carboxylic Acid |
CAS | 22059-21-8 |
EINECS | 606-917-8 |
InChI | InChI=1/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7) |
InChIKey | PAJPWUMXBYXFCZ-UHFFFAOYSA-N |
Molecular Formula | C4H7NO2 |
Molar Mass | 101.1 |
Density | 1.2245 (rough estimate) |
Melting Point | 229-231 °C (lit.) |
Boling Point | 189.47°C (rough estimate) |
Flash Point | 92.2°C |
Water Solubility | Soluble in water. |
Solubility | Soluble in water. |
Vapor Presure | 0.0256mmHg at 25°C |
Appearance | Powder Granules(White to off-white) |
Color | White to off-white |
BRN | 2076413 |
pKa | 2.29±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Stability | Store in freezer at -20°C |
Refractive Index | 1.4340 (estimate) |
MDL | MFCD00009944 |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | GZ1110000 |
HS Code | 29213000 |
Hazard Note | Irritant |
Reference Show more | 1. Liu Xu, Zhou Wennan, Chen Zhao, et al. Effects of Rhizosphere Growth-promoting Bacteria on Germination and Seedling Growth of Aging Seeds of Bromus chinensis [J]. Heilongjiang Animal Husbandry and Veterinary Medicine, 2018, 000(011):24-31. 2. Zhang Liping, Ji Shujuan. Effects of Different Treatments after Cold Storage on Nanguo Pear Esters and Key Enzymes of Ethylene Synthesis Treated with 1-MCP [J]. Food Science, 2013(24):285-288. |
introduction | 1-aminocyclopropane carboxylic acid is a kind of cyclic amino acid, also known as ACC, which is widely found in non-protein amino acids of fruits such as pears and apples. The plant is synthesized by methionine, and ethylene is finally produced through various steps of transformation in the plant. Under the action of related enzymes, 8 is synthesized by S adenosylmethionine in vivo. |
application | 1-aminocyclopropane carboxylic acid is a cyclic amino acid, also known as ACC, which can be used as an intermediate in drug synthesis (mainly polypeptide drugs) and plant growth regulators. |
Preparation | The famous German organic chemist Schoenkopf has achieved excellent results in the study of the synthesis method of 1-aminocyclopropane carboxylic acid and its physiological effects. Schoenkopf in a nitrogen environment, ethyl cyanoacetate and 1, 2-dibromoethane are used to form a ternary ring by NaH, and then 1-aminocyclopropane carboxylate hydrochloride is prepared by hydrochloric acid: |
biological activity | 1-Aminocyclopropane-1-carboxylic acid is an endogenous metabolite. |