1-炔丙基-4-甲基吡啶鎓溴化物 - Names and Identifiers
1-炔丙基-4-甲基吡啶鎓溴化物 - Introduction
bromide is an organic compound whose chemical formula is C8H9BrN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: bromide is a solid substance, usually white to light yellow crystals.
-Solubility: It has low solubility in water, but has better solubility in organic solvents such as methanol, ethanol and dimethyl sulfoxide.
Use:
bromide is often used as a reagent in organic synthesis to catalyze various organic reactions, such as C- C bond formation reactions and C- N bond formation reactions.
-It can also be used as an intermediate in coating chemistry.
Preparation Method:
The synthesis of bromide is generally completed by the following steps:
1.4-methyl pyridine bromide is reacted with propargyl sodium in the presence of potassium carbonate to generate 1-propargyl -4-methyl pyridine.
2. The obtained 1-propargyl-4-methylpyridine is reacted with hydrochloric acid to form a 1-propargyl-4-methylpyridinium salt.
3. Finally, 1-propargyl-methyl pyridinium salt is reacted with benzyl alcohol sodium bromide to form bromide.
Safety Information:
-The bromide should be stored in an airtight container, away from direct contact with air, moisture and sunlight.
-Wear appropriate protective equipment, such as chemical protective gloves and safety glasses.
-When conducting experiments, pay attention to complying with relevant laboratory safety rules and regulations, and avoid direct skin contact and inhalation of its vapor.
-Observe relevant environmental safety regulations when disposing of waste and residues.
Last Update：2024-04-10 22:29:15