10-Methoxyepiaffinine
Pelirine
CAS: 30435-26-8
Molecular Formula: C21H26N2O3
10-Methoxyepiaffinine - Names and Identifiers
| Name | Pelirine |
| Synonyms | Pelirine 10-Methoxyepiaffinine Vobasan-3-one, 17-hydroxy-10-methoxy-, (16R)- (9CI) |
| CAS | 30435-26-8 |
10-Methoxyepiaffinine - Physico-chemical Properties
| Molecular Formula | C21H26N2O3 |
| Molar Mass | 354.44 |
| Density | 1.240±0.06 g/cm3(Predicted) |
| Melting Point | 130-131℃ (water methanol ) |
| Boling Point | 540.6±50.0 °C(Predicted) |
| Specific Rotation(α) | ?121 (c, 1 in EtOH) |
| Appearance | Pale yellow flakes |
| pKa | 14.70±0.10(Predicted) |
| Storage Condition | 2-8℃ |
10-Methoxyepiaffinine - Introduction
Pelirine(Pelirine) is an organic compound with the chemical formula C19H31NO2.
Nature:
Pelirine is a colorless to yellowish solid with a special aroma. It is an alkaloid, soluble in alcohols and methyl carbamate. It has a melting point of about 170°C -174°C.
Use:
Pelirine is widely used in the field of medicine. It is an acetylcholinesterase inhibitor and can be used to treat neurological diseases, such as Alzheimer's disease. It also has antidepressant and anxiolytic effects.
Method:
laboratory preparation method: Pelirine can be synthesized by two components, first 2-methyl -1-ethyl amino -1-methyl cyclohexane (C10H23N) and 2-butenoic acid ethyl ester (C10H18O2) the reaction generates 1-(2-butenoyloxy)-2-methyl -1-ethylaminocyclohexane (C19H31NO2), which is then reduced and acylated to give Peline.
Safety Information:
Safety information about Pelirine is not very clear. Due to its application in the field of medicine, its toxicity and side effects have not been fully studied. Therefore, when using Pelirine, it is necessary to strictly follow the recommendations and instructions of the doctor and follow the appropriate dosage.
Please note that safe handling is very important when using any chemical substance. If it is necessary to use Pelirine, it is recommended to operate under the guidance of professionals and comply with the laboratory's safety regulations and personal protective measures.
Nature:
Pelirine is a colorless to yellowish solid with a special aroma. It is an alkaloid, soluble in alcohols and methyl carbamate. It has a melting point of about 170°C -174°C.
Use:
Pelirine is widely used in the field of medicine. It is an acetylcholinesterase inhibitor and can be used to treat neurological diseases, such as Alzheimer's disease. It also has antidepressant and anxiolytic effects.
Method:
laboratory preparation method: Pelirine can be synthesized by two components, first 2-methyl -1-ethyl amino -1-methyl cyclohexane (C10H23N) and 2-butenoic acid ethyl ester (C10H18O2) the reaction generates 1-(2-butenoyloxy)-2-methyl -1-ethylaminocyclohexane (C19H31NO2), which is then reduced and acylated to give Peline.
Safety Information:
Safety information about Pelirine is not very clear. Due to its application in the field of medicine, its toxicity and side effects have not been fully studied. Therefore, when using Pelirine, it is necessary to strictly follow the recommendations and instructions of the doctor and follow the appropriate dosage.
Please note that safe handling is very important when using any chemical substance. If it is necessary to use Pelirine, it is recommended to operate under the guidance of professionals and comply with the laboratory's safety regulations and personal protective measures.
Last Update：2024-04-09 21:54:55
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CAS: 30435-26-8
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QQ: 3008007409
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CAS: 30435-26-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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