Molecular Formula | C8H6F3NO2 |
Molar Mass | 205.13 |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
3-Trifluoromethylpyridine-2-acetic acid, also known as TFMPA, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: TFMPA is a colorless to light yellow liquid.
-Solubility: It is soluble in organic solvents, such as ethanol and acetone, but insoluble in water.
-Stability: TFMPA is a stable compound with good thermal and chemical stability.
Usage:
-TFMPA is commonly used as an important reagent in organic synthesis. It can be used as a dehydrating agent in the preparation of catalysts, organic reactions, and synthesis.
-It can also be used as an additive for protective bonding agents and coating formulations.
Preparation Method:
The preparation of TFMPA is generally carried out by the following steps:
1. 3-pyridinecarboxaldehyde reacts with trifluoroethyl methyl ether to generate 2-trifluoromethylpyridine.
2. 2-trifluoromethylpyridine is then reacted with acetic anhydride to generate 3-trifluoromethylpyridine-2-acetic acid.
Safety Information:
- TFMPA is an organic substance and needs attention to prevent it from contacting the skin and eyes. Personal protective equipment such as protective gloves and goggles should be worn during operation.
-During storage and use, keep away from fire and high temperature. Store in a cool, ventilated place.
-If inhaled or ingested, seek medical attention immediately.
-During use or disposal, please follow local regulations and safe operating procedures.
Please note that TFMPA has certain toxicity and must be used and handled correctly and in accordance with relevant safe operating procedures. For more details, please refer to the relevant Material Safety Data Sheet (MSDS).