Name | Irinotecan HCL |
Synonyms | Irinotecan HCL Topotecin Hydrochloride Irinotecan Hydrochloride Irinotecan, Hydrochloride |
CAS | 100286-90-6 |
InChI | InChI=1/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1 |
Molecular Formula | C33H38N4O6· HCl |
Molar Mass | 623.14 |
Melting Point | 250-256℃ (dec.) |
Boling Point | 873.4°C at 760 mmHg |
Specific Rotation(α) | 67.7 ° (C=1, H2O) |
Flash Point | 482°C |
Solubility | Slightly soluble in water, ethanol or chloroform, insoluble in acetone |
Vapor Presure | 1.31E-32mmHg at 25°C |
Appearance | Pale yellow powder or light yellow crystalline powder |
Storage Condition | 2-8℃ |
MDL | MFCD01862255 |
Use | Used as an antineoplastic agent |
Reference Show more | 1. Bi, Ye, et al. "Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy." International journal of nanomedicine 13 (2018): 5811.https://dx.doi.org/10.2147%2FIJN.S173279 2. [IF=6.4] Ye Bi et al."Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy."Int J Nanomed. 2018; 13: 5811–5822 |