1004294-80-7

1004294-80-7 - Names and Identifiers

Name	1-Isoindolinone-6-boronic acid pinacol ester
Synonyms	1-Isoindolinone-6-boronic acid pinacol ester isoindolin-1-one-6-boronic acid pinacol ester 1-Oxo-2,3-dihydro-isoindole-6-boronic acid picol ester 1-Oxo-2,3-dihydro-isoindole-6-boronic acid pinacol ester 2,3-Dihydro-1H-isoindol-1-one-6-boronic acid pinacol ester 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one 6-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-2,3- dihydro-1H-isoindol-1-one 1H-Isoindol-1-one, 2,3-dihydro-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 1H-Isoindol-1-one, 2,3-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	1004294-80-7

1004294-80-7 - Physico-chemical Properties

Molecular Formula	C14H18BNO3
Molar Mass	259.11
Density	1.16±0.1 g/cm3(Predicted)
Boling Point	466.8±45.0 °C(Predicted)
Flash Point	236.1 °C
pKa	13.91±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Irritant
MDL	MFCD11849992

1004294-80-7 - Introduction

1-Isoindolone-6-boronic acid pinacol ester is an organic compound with the chemical formula C12H11BO4. It is a colorless crystalline powder that dissolves in solvents. The following is a description of some properties, uses, preparation and safety information about the compound:

Nature:
1-isoindolone-6-boronic acid pinacol ester has high thermal stability and solubility. It is a functional organoboron compound containing pinacol group and boronic acid group. In chemical reactions, pinacol groups and boronic acid groups may play the role of catalysts, stabilizers and ligands.

Use:
1-isoindolone-6-boronic acid pinacol ester is widely used in organic synthesis and homogeneous catalysis. As a ligand, it forms complexes with transition metals and participates in metal-catalyzed reactions, such as asymmetric hydrogenation, asymmetric amino reduction, and epoxidation. In addition, it is also used as a stabilizer and functional reagents, such as infrared luminescent agents, fluorescent dyes and biological analysis reagents.

Preparation Method:
1-isoindolone-6-boronic acid pinacol ester can be prepared by chemical synthesis. One commonly used method is the reaction of pinacol diborate with isoindolone to produce the desired product. Specific synthesis steps need to carry out the relevant experimental operation and condition control.

Safety Information:
1-isoindolone-6-boronic acid pinacol ester is a relatively safe compound under general use conditions. However, as an organic compound, it still needs to be used with caution. Avoid skin contact, inhalation and ingestion during operation. It is recommended to operate in well-ventilated laboratory conditions and to wear appropriate personal protective equipment. If accidental contact occurs, immediately flush the affected area with plenty of water and, if necessary, seek medical help.

Last Update：2024-04-10 22:29:15