100516-71-0
2-Thiazolecarbonitrile, 5-methyl-
CAS: 100516-71-0
Molecular Formula: C5H4N2S
100516-71-0 - Names and Identifiers
| Name | 2-Thiazolecarbonitrile, 5-methyl- |
| Synonyms | 2-Cyano-5-methylthiazole 5-Methyl-thiazole-2-carbonitrile 2-Thiazolecarbonitrile, 5-methyl- 2-Thiazolecarbonitrile, 5-methyl- |
| CAS | 100516-71-0 |
| InChI | InChI=1/C5H4N2S/c1-4-3-7-5(2-6)8-4/h3H,1H3 |
100516-71-0 - Physico-chemical Properties
| Molecular Formula | C5H4N2S |
| Molar Mass | 124.16 |
| Refractive Index | 1.559 |
100516-71-0 - Introduction
5-Methylthiazole-2-carbonitrile is an organic compound whose chemical formula is C5H6N2S. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 5-methyl thiazole -2-carbonitrile is a colorless liquid.
2. solubility: soluble in water, ethanol and ether and other common organic solvents.
3. stability: relatively stable at room temperature, but will be affected by heat and light.
4. toxicity: has a certain toxicity, need to be careful handling and storage.
Use:
1. chemical raw materials: 5-methylthiazole-2-carbonitrile can be used as raw materials for the synthesis of other organic compounds.
2. pesticide intermediates: in the synthesis of pesticides, often used as intermediates or catalysts.
Preparation Method:
The preparation method of 5-methylthiazole-2-carbonitrile can be obtained by the condensation reaction of synthetic ammonia and 3-mercaptopropionic acid. Specific steps are as follows:
1. Condensation of 3-mercaptopropionic acid and aldehydes under alkaline conditions to generate 5-mercapto -2-oxo-Δ ^ 2-thiazolidine.
2. The product was dehydrated under acidic conditions to obtain 5-mercaptothiazole.
3. Finally, 5-mercaptothiazole is converted to 5-methylthiazole-2-carbonitrile by cyanation reaction.
Safety Information:
1. 5-Methylthiazole-2-carbonitrile has certain toxicity. Avoid contact with skin and eyes, and ensure that it is operated in a well-ventilated place.
2. in case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. in the process of storage and transportation, should avoid contact with oxidants, acids, corrosive substances and other substances, avoid fire and high temperature.
4. For detailed safety operation information, please refer to the relevant safety data sheet.
Nature:
1. Appearance: 5-methyl thiazole -2-carbonitrile is a colorless liquid.
2. solubility: soluble in water, ethanol and ether and other common organic solvents.
3. stability: relatively stable at room temperature, but will be affected by heat and light.
4. toxicity: has a certain toxicity, need to be careful handling and storage.
Use:
1. chemical raw materials: 5-methylthiazole-2-carbonitrile can be used as raw materials for the synthesis of other organic compounds.
2. pesticide intermediates: in the synthesis of pesticides, often used as intermediates or catalysts.
Preparation Method:
The preparation method of 5-methylthiazole-2-carbonitrile can be obtained by the condensation reaction of synthetic ammonia and 3-mercaptopropionic acid. Specific steps are as follows:
1. Condensation of 3-mercaptopropionic acid and aldehydes under alkaline conditions to generate 5-mercapto -2-oxo-Δ ^ 2-thiazolidine.
2. The product was dehydrated under acidic conditions to obtain 5-mercaptothiazole.
3. Finally, 5-mercaptothiazole is converted to 5-methylthiazole-2-carbonitrile by cyanation reaction.
Safety Information:
1. 5-Methylthiazole-2-carbonitrile has certain toxicity. Avoid contact with skin and eyes, and ensure that it is operated in a well-ventilated place.
2. in case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. in the process of storage and transportation, should avoid contact with oxidants, acids, corrosive substances and other substances, avoid fire and high temperature.
4. For detailed safety operation information, please refer to the relevant safety data sheet.
Last Update：2024-04-10 22:29:15
