1008493-30-8
Isopropyl 2-(3-oxo-2-piperazinyl)acetate
CAS: 1008493-30-8
Molecular Formula: C9H16N2O3
1008493-30-8 - Names and Identifiers
1008493-30-8 - Physico-chemical Properties
| Molecular Formula | C9H16N2O3 |
| Molar Mass | 200.23 |
| Density | 1.076±0.06 g/cm3(Predicted) |
| Boling Point | 362.7±27.0 °C(Predicted) |
| pKa | 15.08±0.40(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD05666704 |
1008493-30-8 - Introduction
Isopropyl 2-(3-oxo-2-piperazinyl)acetate (isopropyl 2-(3-oxo-2-piperazinyl)acetate) is an organic compound. The following is its nature, use, preparation and safety information:
Nature:
Isopropyl 2-(3-oxo-2-piperazinyl)acetate is a white crystal or crystalline powder with a special smell. Its relative molecular mass is about 186.22g/mol. It is stable at room temperature.
Use:
Isopropyl 2-(3-oxo-2-piperazinyl)acetate is widely used in the pharmaceutical field, especially as an intermediate for the synthesis of various drugs. It can be used in the synthesis of polypeptides, amino acid derivatives, drug ligands, etc.
Preparation Method:
The preparation method of Isopropyl 2-(3-oxo-2-piperazinyl)acetate is generally completed by condensation reaction of isopropyl acetoxyacetate and 2-hydroxypiperazine. Specific methods are as follows:
1. Mix isopropyl acetoxyacetate with 2-hydroxypiperazine in a suitable reaction solvent.
2. Add a base catalyst, such as triethylamine, and carry out the reaction at an appropriate temperature.
3. After completion of the reaction, the mixture was purified and crystallized to obtain a pure product.
Safety Information:
Pay attention to the following safety information when using Isopropyl 2-(3-oxo-2-pipeazinyl) acetate:
1. It is a chemical substance that is irritating to the eyes, skin and respiratory system. Wear protective goggles, gloves and respiratory protective equipment during use.
2. avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
3. in the operation should ensure good ventilation conditions, avoid inhalation of its vapor.
4. storage should be away from fire and oxidant, avoid high temperature and direct sunlight.
5. Please read and follow the safety instructions of the product before use.
Please note that Isopropyl 2-(3-oxo-2-piperazinyl)acetate is a chemical substance and should be used with caution and follow relevant safety procedures.
Nature:
Isopropyl 2-(3-oxo-2-piperazinyl)acetate is a white crystal or crystalline powder with a special smell. Its relative molecular mass is about 186.22g/mol. It is stable at room temperature.
Use:
Isopropyl 2-(3-oxo-2-piperazinyl)acetate is widely used in the pharmaceutical field, especially as an intermediate for the synthesis of various drugs. It can be used in the synthesis of polypeptides, amino acid derivatives, drug ligands, etc.
Preparation Method:
The preparation method of Isopropyl 2-(3-oxo-2-piperazinyl)acetate is generally completed by condensation reaction of isopropyl acetoxyacetate and 2-hydroxypiperazine. Specific methods are as follows:
1. Mix isopropyl acetoxyacetate with 2-hydroxypiperazine in a suitable reaction solvent.
2. Add a base catalyst, such as triethylamine, and carry out the reaction at an appropriate temperature.
3. After completion of the reaction, the mixture was purified and crystallized to obtain a pure product.
Safety Information:
Pay attention to the following safety information when using Isopropyl 2-(3-oxo-2-pipeazinyl) acetate:
1. It is a chemical substance that is irritating to the eyes, skin and respiratory system. Wear protective goggles, gloves and respiratory protective equipment during use.
2. avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
3. in the operation should ensure good ventilation conditions, avoid inhalation of its vapor.
4. storage should be away from fire and oxidant, avoid high temperature and direct sunlight.
5. Please read and follow the safety instructions of the product before use.
Please note that Isopropyl 2-(3-oxo-2-piperazinyl)acetate is a chemical substance and should be used with caution and follow relevant safety procedures.
Last Update：2024-04-09 15:18:10
