101084-20-2
3-Amino-5-bromopyridin-4-ol
CAS: 101084-20-2
Molecular Formula: C5H5BrN2O
101084-20-2 - Names and Identifiers
| Name | 3-Amino-5-bromopyridin-4-ol |
| Synonyms | 3-Amino-5-bromopyridin-4-ol 3-AMINO-5-BROMOPYRIDIN-4-OL 3-Amino-5-bromo-4-pyridinol 3-Amino-5-bromo-pyridin-4-oI 3-AMINO-5-BROMO-PYRIDIN-4-OL 4-Pyridinol, 3-amino-5-bromo- 3-amino-5-bromo-1H-pyridin-4-one 3-Amino-5-bromo-4-hydroxypyridine |
| CAS | 101084-20-2 |
| InChI | InChI=1S/C5H5BrN2O/c6-3-1-8-2-4(7)5(3)9/h1-2H,7H2,(H,8,9) |
101084-20-2 - Physico-chemical Properties
| Molecular Formula | C5H5BrN2O |
| Molar Mass | 189.01 |
| Density | 1.898 |
| Melting Point | 230 °C (decomp)(Solv: water (7732-18-5)) |
| Boling Point | 434.6±45.0 °C(Predicted) |
| Appearance | Solid |
| pKa | 3.51±0.23(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
101084-20-2 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
101084-20-2 - Introduction
3-Amino-4-hydroxy-5-bromopyridine is an organic compound with the chemical formula C5H5BrN2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-amino-4-hydroxy-5-bromopyridine is a colorless to pale yellow crystal or crystalline powder.
-Melting point: approximately 200-205°C.
-Solubility: It can be dissolved in water and stable under alkaline conditions.
Use:
-Pharmaceutical field: 3-amino-4-hydroxy-5-bromopyridine is an important intermediate compound commonly used in the synthesis of drugs, such as acetaminophen and antiepileptic drugs.
-Agricultural field: It can also be used for the synthesis of pesticides.
Preparation Method:
The preparation of 3-amino-4-hydroxy-5-bromopyridine can be carried out by the following steps:
1. 3-bromo-4-methoxy-5-nitropyridine is reacted with ammonia to obtain 3-bromo-4-methoxy-5-aminopyridine.
2. 3-bromo-4-methoxy-5-aminopyridine is reacted with sodium hydroxide to obtain 3-bromo-4-methoxy-5-hydroxypyridine.
3. 3-Bromo-4-methoxy-5-hydroxypyridine is reacted with ammonium chloride to obtain 3-amino-4-hydroxy-5-bromopyridine.
Safety Information:
-3-Amino-4-hydroxy-5-bromopyridine is an organic compound, and care should be taken to avoid contact with eyes, skin and administration.
-Wear suitable personal protective equipment, such as gloves and protective glasses.
-Keep away from fire and heat sources during use and storage.
-Waste to be disposed of in accordance with local regulations.
Nature:
-Appearance: 3-amino-4-hydroxy-5-bromopyridine is a colorless to pale yellow crystal or crystalline powder.
-Melting point: approximately 200-205°C.
-Solubility: It can be dissolved in water and stable under alkaline conditions.
Use:
-Pharmaceutical field: 3-amino-4-hydroxy-5-bromopyridine is an important intermediate compound commonly used in the synthesis of drugs, such as acetaminophen and antiepileptic drugs.
-Agricultural field: It can also be used for the synthesis of pesticides.
Preparation Method:
The preparation of 3-amino-4-hydroxy-5-bromopyridine can be carried out by the following steps:
1. 3-bromo-4-methoxy-5-nitropyridine is reacted with ammonia to obtain 3-bromo-4-methoxy-5-aminopyridine.
2. 3-bromo-4-methoxy-5-aminopyridine is reacted with sodium hydroxide to obtain 3-bromo-4-methoxy-5-hydroxypyridine.
3. 3-Bromo-4-methoxy-5-hydroxypyridine is reacted with ammonium chloride to obtain 3-amino-4-hydroxy-5-bromopyridine.
Safety Information:
-3-Amino-4-hydroxy-5-bromopyridine is an organic compound, and care should be taken to avoid contact with eyes, skin and administration.
-Wear suitable personal protective equipment, such as gloves and protective glasses.
-Keep away from fire and heat sources during use and storage.
-Waste to be disposed of in accordance with local regulations.
Last Update：2024-04-09 02:00:40
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Product Name: 3-Amino-5-Bromo-Pyridin-4-OL Visit Supplier Webpage Request for quotation
CAS: 101084-20-2
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QQ: 3008007409
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CAS: 101084-20-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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