10130-87-7

10130-87-7 - Names and Identifiers

Name	2-Methoxybenzenesulfonyl Chloride
Synonyms	AKOS BB-9465 2-Methoxyphenylsulfonyl chloride 5-Methoxybenzenesulfonyl chloride 2-METHOXYBENZENESULFONYL CHLORIDE 2-Methoxybenzenesulfonyl Chloride o-Methoxybenzenesulfonyl chloride 2-Methoxybenzene-1-sulfonyl chloride 2-(Methyloxy)benzenesulfonyl chloride M**2-METHOXYBENZENE SULFONYL CHLORIDE
CAS	10130-87-7
InChI	InChI=1/C7H7ClO3S/c1-11-6-4-2-3-5-7(6)12(8,9)10/h2-5H,1H3

10130-87-7 - Physico-chemical Properties

Molecular Formula	C7H7ClO3S
Molar Mass	206.65
Density	1.376
Melting Point	50-54°C
Boling Point	126-129 °C(Press: 0.3 Torr)
Flash Point	138.3°C
Vapor Presure	0.00152mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Moisture Sensitive
Refractive Index	1.535

10130-87-7 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R34 - Causes burns R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	3261
Hazard Class	IRRITANT
Packing Group	Ⅲ

10130-87-7 - Introduction

2-Methoxybenzenesulfonyl chloride is an organic compound with the chemical formula C8H9ClO3S. Its properties are as follows:

1. Appearance: 2-methoxybenzenesulfonyl chloride is a colorless to pink crystalline solid.
2. Solubility: It is insoluble in water, but soluble in organic solvents such as ether, chloroform and alcohols.
3. smell: it has a spicy smell.

2-methoxybenzenesulfonyl chloride is commonly used in organic synthesis and pharmaceutical fields, and its main uses include:
1. can be used as benzene sulfonic acid ester synthesis reagent.
2. It can be used as a deprotecting reagent and a chlorinating agent in the synthesis of drugs, especially amino acid derivatives and drug intermediates.
3. It can also be used as a synthetic reagent for dyes and pigments.

The preparation method of 2-methoxybenzenesulfonyl chloride is generally to react methoxybenzenesulfonic acid with thionyl chloride under appropriate reaction conditions to generate 2-methoxybenzenesulfonyl chloride.

When using 2-methoxybenzenesulfonyl chloride, you need to pay attention to the following safety information:
1. It is an organic synthetic reagent and should avoid direct contact with skin, eyes and mouth.
2. During operation, it should be carried out in a well-ventilated place to avoid inhaling its steam or dust.
3. Use personal protective equipment such as protective gloves, goggles and protective clothing.
4. For detailed safety information about the specific operation and handling of the compound, it is recommended to check the relevant safety data sheet.

Last Update：2024-04-09 19:05:44