1017241-34-7 - Names and Identifiers
1017241-34-7 - Physico-chemical Properties
Molecular Formula | C17H20N4O2
|
Molar Mass | 312.37 |
Density | 1.27±0.1 g/cm3(Predicted) |
Melting Point | 188-191°C |
Solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Sligh |
Appearance | Solid |
Color | Light Yellow to Yellow |
pKa | 10.45±0.40(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Stability | Hygroscopic |
1017241-34-7 - Risk and Safety
1017241-34-7 - Introduction
Olanzapine Lactam Impurity(Olanzapine Lactam Impurity) is a specific Impurity of Olanzapine (Olanzapine). Olanzapine is an antipsychotic drug, belonging to the benzodiazepine class of drugs. Olanzapine Lactam Impurity is a Lactam compound produced by the decomposition of Olanzapine.
The chemical properties of Olanzapine Lactam Impurity are relatively stable, and its molecular structure is similar to Olanzapine. However, the toxicity of Olanzapine Lactam Impurity may be different from Olanzapine, so it needs to be monitored and controlled.
In the pharmaceutical industry, the content of Olanzapine Lactam Impurity needs to be strictly controlled because it may have an impact on the safety and effectiveness of Olanzapine drugs. The lower the content of Olanzapine Lactam Impurity, the higher the quality of the drug.
The preparation method of Olanzapine Lactam Impurity is mainly through the acid-catalyzed isomerization reaction of Olanzapine under specific conditions to generate Lactam compounds. The preparation process needs to control the reaction conditions, such as temperature, reaction time and catalyst concentration, to ensure the yield and purity.
Regarding the safety information of Olanzapine Lactam Impurity, because its toxicity may be different from Olanzapine itself, strict toxicity evaluation and safety studies are required. When using olanzapine drugs, it is necessary to ensure that the content of impurities meets regulatory requirements to ensure the safety and effectiveness of the drug. At the same time, the production and use of Olanzapine Lactam Impurity also requires compliance with chemical safety practices and appropriate protective measures to protect the health and safety of workers.
Last Update:2024-04-09 21:54:55