101930-07-8
(R)-(+)-N-benzyl 3-hydroxypyrrolidine
CAS: 101930-07-8
Molecular Formula: C11H15NO
101930-07-8 - Names and Identifiers
101930-07-8 - Physico-chemical Properties
| Molecular Formula | C11H15NO |
| Molar Mass | 177.24 |
| Density | 1.07g/mLat 25°C(lit.) |
| Boling Point | 116°C0.9mm Hg(lit.) |
| Specific Rotation(α) | 3.7 º (c=5, MeOH) |
| Flash Point | >230°F |
| Vapor Presure | 0.000592mmHg at 25°C |
| Specific Gravity | 1.07 |
| pKa | 14.82±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.548(lit.) |
| Physical and Chemical Properties | Density 1.07 Boiling point 116°C (0.9 mmHg) Refractive index 1.548 Flash point >110°C alpha 3.7° (c=5, MeOH) |
101930-07-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29339900 |
101930-07-8 - Introduction
(R)-(+)-1-benzyl-3-pyrrolidinol, also known as (R)-benzyl-3-pyrrolidinol, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Properties:(R)-( )-1-benzyl-3-pyrrolidinol is a solid, usually colorless or light yellow crystals. It is the (R)-enantiomer in optical isomers, and its chiral nature affects the selectivity of some chemical reactions. The compounds are soluble in many organic solvents, such as alcohols and ketones, at ambient temperatures.
Uses:(R)-( )-1-benzyl-3-pyrrolidinol has important applications in organic synthesis. It can be used as a chiral inducer for asymmetric catalytic reactions, such as asymmetric nucleophilic substitution, dehydration and etherification reactions. This compound can also be used as an intermediate for the synthesis of drugs and for the preparation of other biologically active compounds.
Preparation method:(R)-( )-1-benzyl-3-pyrrolidinol can be synthesized by various methods, one of which is commonly used by liquid-phase catalytic asymmetric hydrogenation. By selecting the appropriate catalyst and reaction conditions, a highly stereoselective product synthesis can be achieved.
Safety Information: General laboratory safety practices should be followed when using or handling (R)-( )-1-benzyl-3-pyrrolidinol. It may be an irritant to the eyes, skin and respiratory system, so contact needs to be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. In addition, it should be stored in a closed container, away from high temperature and fire sources to avoid the risk of fire and explosion. If necessary, it is recommended to use under professional guidance.
Properties:(R)-( )-1-benzyl-3-pyrrolidinol is a solid, usually colorless or light yellow crystals. It is the (R)-enantiomer in optical isomers, and its chiral nature affects the selectivity of some chemical reactions. The compounds are soluble in many organic solvents, such as alcohols and ketones, at ambient temperatures.
Uses:(R)-( )-1-benzyl-3-pyrrolidinol has important applications in organic synthesis. It can be used as a chiral inducer for asymmetric catalytic reactions, such as asymmetric nucleophilic substitution, dehydration and etherification reactions. This compound can also be used as an intermediate for the synthesis of drugs and for the preparation of other biologically active compounds.
Preparation method:(R)-( )-1-benzyl-3-pyrrolidinol can be synthesized by various methods, one of which is commonly used by liquid-phase catalytic asymmetric hydrogenation. By selecting the appropriate catalyst and reaction conditions, a highly stereoselective product synthesis can be achieved.
Safety Information: General laboratory safety practices should be followed when using or handling (R)-( )-1-benzyl-3-pyrrolidinol. It may be an irritant to the eyes, skin and respiratory system, so contact needs to be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. In addition, it should be stored in a closed container, away from high temperature and fire sources to avoid the risk of fire and explosion. If necessary, it is recommended to use under professional guidance.
Last Update：2024-04-09 20:52:54
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Product Name: (R)-(+)-N-benzyl 3-hydroxypyrrolidine Request for quotation
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CAS: 101930-07-8
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