1020253-21-7
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine
CAS: 1020253-21-7
Molecular Formula: C6H3ClFN3
1020253-21-7 - Names and Identifiers
| Name | 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine |
| Synonyms | 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine 1,2,4-Triazolo[4,3-a]pyridine, 6-chloro-8-fluoro- |
| CAS | 1020253-21-7 |
1020253-21-7 - Physico-chemical Properties
| Molecular Formula | C6H3ClFN3 |
| Molar Mass | 171.56 |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD09972195 |
1020253-21-7 - Introduction
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine is an organic compound with the chemical formula C7H3ClFN4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine is a solid, the common form is white crystals.
-Melting point: The melting point of the compound is approximately 158-160 degrees Celsius.
-Solubility: It has good solubility in common organic solvents.
Use:
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine is often used as an important intermediate in organic synthesis for the synthesis of other compounds. It also has some applications in the pharmaceutical field as an intermediate for antibacterial and antifungal drugs.
Preparation Method:
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine has many preparation methods, but one of the common methods is to react a mixture of aniline, zinc chloride and stannous fluoride with 2,4-dinitrotrichlorobenzene to obtain an intermediate, and then to obtain the target product through dehydration and cyclization reaction.
Safety Information:
When handling 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine, use appropriate personal protective measures, such as gloves and safety glasses. Avoid contact with skin and eyes, and avoid inhaling its dust or vapor. Provide good ventilation during operation. In addition, the waste of the compound is sealed and properly disposed of to ensure safety. In case of any accident, seek medical assistance immediately.
Nature:
-Appearance: 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine is a solid, the common form is white crystals.
-Melting point: The melting point of the compound is approximately 158-160 degrees Celsius.
-Solubility: It has good solubility in common organic solvents.
Use:
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine is often used as an important intermediate in organic synthesis for the synthesis of other compounds. It also has some applications in the pharmaceutical field as an intermediate for antibacterial and antifungal drugs.
Preparation Method:
6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine has many preparation methods, but one of the common methods is to react a mixture of aniline, zinc chloride and stannous fluoride with 2,4-dinitrotrichlorobenzene to obtain an intermediate, and then to obtain the target product through dehydration and cyclization reaction.
Safety Information:
When handling 6-Chloro-8-fluoro-[1,2,4]triazolo[4,3-a]pyridine, use appropriate personal protective measures, such as gloves and safety glasses. Avoid contact with skin and eyes, and avoid inhaling its dust or vapor. Provide good ventilation during operation. In addition, the waste of the compound is sealed and properly disposed of to ensure safety. In case of any accident, seek medical assistance immediately.
Last Update：2024-04-09 20:52:54
