Name | Tyrosine kinase inhibitor |
Synonyms | CS-938 DCL000409 DCL000409(XL184) Tyrosine kinase inhibitor 1-Cyclopropanedicarboxamide 3-b]pyridin-4-yl]oxy]phenyl]- N-(4-fluorophenyl)-N-(4-((2-((2-morpholinoethyl)carbamoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide N-(4-Fluorophenyl)-N'-[4-[[2-[[[2-(4-morpholinyl)ethyl]amino]carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-1,1-cyclopropanedicarboxamide 1,1-CyclopropanedicarboxaMide, N-(4-fluorophenyl)-N'-[4-[[2-[[[2-(4-Morpholinyl)ethyl]aMino]carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]- |
CAS | 1021950-26-4 |
Molecular Formula | C31H31FN6O5 |
Molar Mass | 586.61 |
Density | 1.428 |
Solubility | DMSO: ≥ 46 mg/mL |
pKa | 12.22±0.40(Predicted) |
Storage Condition | -20℃ |
In vitro study | Tyrosine kinases are important mediators of the signaling cascade, determining key roles in diverse biological processes like growth, differentiation, metabolism and apoptosis in response to external and internal stimuli. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.705 ml | 8.523 ml | 17.047 ml |
5 mM | 0.341 ml | 1.705 ml | 3.409 ml |
10 mM | 0.17 ml | 0.852 ml | 1.705 ml |
5 mM | 0.034 ml | 0.17 ml | 0.341 ml |