10300-27-3

10300-27-3 - Names and Identifiers

Name	3'-O-Methyl-Guanosine
Synonyms	3-OMG 3'-OMe-G 3'-O-Me-Gr NSC 106541 3'-O-Methylguanosine 3'-O-Methyl-Guanosine Guanosine, 3'-O-methyl- 3'-O-methylguanosine top3 2-amino-9-(3-O-methylpentofuranosyl)-3,9-dihydro-6H-purin-6-one 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one 2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxy methyl)-4-methoxy tetra hydrofuran-2-yl)-1H-purin-6(9H)-one
CAS	10300-27-3
InChI	InChI=1/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)

10300-27-3 - Physico-chemical Properties

Molecular Formula	C11H15N5O5
Molar Mass	297.27
Density	1.98±0.1 g/cm3(Predicted)
Melting Point	263-300 °C (decomp)
Boling Point	711.7°C at 760 mmHg
Flash Point	384.2°C
Vapor Presure	2.93E-21mmHg at 25°C
pKa	9?+-.0.20(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.829

10300-27-3 - Introduction

3 '-Methoxyguanosine (3'-Methylguanosine) is a nucleoside whose chemical formula is C11H15N5O5. It is the product of the reaction of the 3 '-hydroxyl site of guanosine with methanol. The following is a description of the properties, uses, preparation and safety information of 3 '-methoxyguanosine:

Nature:
-Appearance: White or almost white crystalline powder.
-Solubility: Soluble in water and methanol.

Use:
-Biochemistry: 3 '-Methoxyguanosine is commonly used to study the structure and function of RNA.
-Antiviral drug development: 3 '-methoxyguanosine has potential use in the development of antiviral drugs.

Preparation Method:
-A common preparation method is to obtain 3 '-methoxyguanosine by reacting guanosine with methanol under alkaline conditions.

Safety Information:
There is no clear information on the toxicity and danger of -3 '-methoxyguanosine, but as a chemical substance, attention should be paid to follow laboratory safety procedures.
-When handling 3 '-methoxyguanosine, it is recommended to wear suitable personal protective equipment, such as gloves, goggles, etc., to avoid direct contact or inhalation.
-Avoid exposing 3 '-methoxyguanosine to high temperatures, fire sources, or strong oxidants to prevent fire or explosion.
-Waste should be disposed of in accordance with local regulations.

Last Update：2024-04-09 15:17:50