103476-89-7

103476-89-7 - Names and Identifiers

Name	Leupeptin
Synonyms	NK-381 C01591 Leupeptin LEUPEPTIN AC-LLR-CHO Leupeptin Ac-LL AC-LEU-LEU-ARG-CHO AC-LEU-LEU-ARGININAL AC-LEU-LEU-L-ARGININAL Acetyl-L-leucyl-L-leucylargininal N-Acetyl-L-leucyl-L-leucyl-L-argininal leupeptin hemisulfate from microbial*source Ac-L-Leu-L-Leu-(1-Formyl-4-guanidinobutyl)-NH2 N-Acetyl-L-Leu-L-Leu-[4-[(aminoiminomethyl)amino]-1-formylbutyl]NH2 L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)- Nα-(N-Acetyl-L-leucyl)-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-leucinamide 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide Valeramide, 2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methyl- N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name)
CAS	24365-47-7 103476-89-7
InChI	InChI=1/C20H38N6O4/c1-12(2)9-16(24-14(5)28)18(29)26-19(30)17(10-13(3)4)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17,25H,6-10H2,1-5H3,(H,24,28)(H4,21,22,23)(H,26,29,30)/t15?,16-,17-/m0/s1

103476-89-7 - Physico-chemical Properties

Molecular Formula	C20H38N6O4
Molar Mass	426.55
Density	1.1865 (rough estimate)
Boling Point	541.98°C (rough estimate)
Solubility	Soluble in water, methanol, ethanol, butanol, dimethyl sulfoxide, insoluble in ethyl acetate, acetone, chloroform, hexane, etc.
Appearance	White or white-like powder
pKa	13.44±0.46(Predicted)
Storage Condition	-20℃
Refractive Index	1.6000 (estimate)
MDL	MFCD00037012
Use	It can inhibit trypsin, papain, tissue egg enzyme B, plasmin, kallikrein, etc. Its inhibitory effect is competitive with the substrate. Can inhibit a variety of serine and cysteine proteases.

103476-89-7 - Reference

Reference

1. [IF=12.27] Yan Gong et al."Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells."Dev Cell. 2021 Jul;56:2103

103476-89-7 - Introduction

It reacted to Rydon-Smith and Sakaguchi, and was positive for ninhydrin, ferric chloride, anthrone, and Molly.

Last Update：2022-10-16 17:15:13

103476-89-7 - Trait

White or off-white powder.

Last Update：2023-08-16 21:32:38

103476-89-7 - Source

Trypsin inhibitor produced by Streptomyces roseus MB-26-AI, one of a number of protease inhibitors.

Last Update：2023-08-16 21:32:38

Shanghai Yuanye Bio-Technology Co., Ltd.

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CAS: 103476-89-7
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Shanghai Yuanye Bio-Technology Co., Ltd.

Spot supply

Product Name: Leupeptin Visit Supplier Webpage Request for quotation
CAS: 103476-89-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

103476-89-7

103476-89-7

Leupeptin

CAS: 24365-47-7;103476-89-7

Molecular Formula: C20H38N6O4

103476-89-7 - Names and Identifiers

103476-89-7 - Physico-chemical Properties

103476-89-7 - Reference

103476-89-7 - Introduction

103476-89-7 - Trait

103476-89-7 - Source

Supplier List

103476-89-7 Request for Quotation

Leupeptin

CAS: 24365-47-7;103476-89-7

Molecular Formula: C20H38N6O4

103476-89-7 - Names and Identifiers

103476-89-7 - Physico-chemical Properties

103476-89-7 - Reference

103476-89-7 - Introduction

103476-89-7 - Trait

103476-89-7 - Source

Supplier List

103476-89-7